Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.44 |
| ▸ | PPARD | Q03181 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.40 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.40 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | ERN1 | O75460 | 2/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | MC4R | P32245 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | PTPRC | P08575 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9258741 | 0.90 | HTR1A (0.41) | PRMT6PPARDKDRERN1HTR1A | |
| SCHEMBL9253601 | 0.85 | PRMT6 (0.43) | PRMT6PPARDCYP2A6CYP2E1CYP2B6 | |
| SCHEMBL9174629 | 0.85 | PRMT6 (0.39) | PRMT6PPARDCYP2A6CYP2E1CYP2B6 | |
| SCHEMBL9254796 | 0.82 | PRMT6 (0.39) | PRMT6PPARDCYP2A6CYP2E1CYP2B6 | |
| SCHEMBL9254793 | 0.82 | PRMT6 (0.39) | PRMT6PPARDCYP2A6CYP2E1CYP2B6 | |
| SCHEMBL9257607 | 0.82 | ALDH1A1 (0.47) | PRMT6PPARDCYP2A6CYP2E1CYP2B6 | |
| SCHEMBL9258901 | 0.82 | LTB4R (0.41) | PPARDLTB4RMC4RHDAC1HDAC2 | |
| SCHEMBL9258896 | 0.82 | LTB4R (0.41) | PPARDLTB4RMC4RHDAC1HDAC2 | |
| SCHEMBL9254689 | 0.82 | PRMT6 (0.40) | PRMT6PPARDCYP2A6CYP2E1CYP2B6 | |
| SCHEMBL5254178 | 0.82 | LTA4H (0.53) | PPARDHDAC1HDAC2HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5439932-A | Anticholesterol agents | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1995-08-08 | — | — | US | disclosed |
| US-5306728-A | Substituted amine derivatives having antihyperlipemia activity | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1994-04-26 | — | — | US | disclosed |
| EP-0448078-A2 | Substituted amine derivatives having anti-hyperlipemia activity | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1991-09-25 | — | — | EP | disclosed |