Sugi Predict

Sugi Predict / Compounds / SCHEMBL9259618

SCHEMBL9259618

SCHEMBL9259618

CCOC(=O)c1csc(C(F)(F)C(F)(F)F)n1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ RAB9A P51151 8/20 0.56
▸ MAPT P10636 7/20 0.56
▸ NPC1 O15118 6/20 0.56
▸ ALDH1A1 P00352 3/20 0.56
▸ MEN1 O00255 1/20 0.56
▸ KMT2A Q03164 1/20 0.56
▸ CYP1A2 P05177 2/20 0.51
▸ CYP2C19 P33261 1/20 0.51
▸ GAA P10253 3/20 0.51
▸ SMN1; SMN2 Q16637 5/20 0.49
▸ NPSR1 Q6W5P4 2/20 0.48
▸ POLB P06746 1/20 0.48
▸ PKM P14618 1/20 0.48
▸ RXFP1 Q9HBX9 1/20 0.48
▸ HSP90AA1 P07900 2/20 0.46
▸ TDP1 Q9NUW8 2/20 0.44
▸ MAPK1 P28482 1/20 0.43
▸ KDM4E B2RXH2 2/20 0.42
▸ LMNA P02545 1/20 0.42
▸ HPGD P15428 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1431668 0.88 RAB9A (0.59) RAB9AMAPTNPC1ALDH1A1MEN1
SCHEMBL1421878 0.83 RAB9A (0.60) RAB9AMAPTNPC1ALDH1A1MEN1
SCHEMBL14292709 0.82 RAB9A (0.63) RAB9AMAPTNPC1ALDH1A1MEN1
SCHEMBL23026451 0.79 RAB9A (0.56) RAB9AMAPTNPC1ALDH1A1MEN1
SCHEMBL13999812 0.79 RAB9A (0.56) RAB9AMAPTNPC1ALDH1A1MEN1
SCHEMBL18412921 0.78 KDM1A (0.40) RAB9AMAPTNPC1ALDH1A1GAA
SCHEMBL2079452 0.77 RAB9A (0.54) RAB9AMAPTNPC1ALDH1A1MEN1
SCHEMBL2523625 0.77 RAB9A (0.54) RAB9AMAPTNPC1ALDH1A1MEN1
SCHEMBL2140026 0.77 RAB9A (0.56) RAB9AMAPTNPC1ALDH1A1MEN1
SCHEMBL9268196 0.76 RAB9A (0.64) RAB9AMAPTNPC1ALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12297209-B2 Benzodiazepine derivatives as RSV inhibitors ENANTA PHARMACEUTICALS, INC. (US) 2025-05-13 — — US disclosed
US-12268694-B2 Combination pharmaceutical agents as RSV inhibitors ENANTA PHARMACEUTICALS, INC. (US) 2025-04-08 — — US disclosed
US-20240360155-A1 Benzodiazepine Derivatives as RSV Inhibitors ENANTA PHARM INC (US) 2024-10-31 — — US disclosed
US-11952389-B2 Benzodiazepine derivatives as RSV inhibitors ENANTA PHARMACEUTICALS, INC. (US) 2024-04-09 — — US disclosed
EP-3687543-B1 COMBINATIONS OF PHARMACEUTICAL AGENTS AS RSV INHIBITORS ENANTA PHARM INC (US) 2024-03-20 — — EP disclosed
CN-111386118-B Combination pharmaceutical agents as RSV inhibitors 英安塔制药有限公司 2023-05-09 — — CN disclosed
US-20230087410-A1 BENZODIAZEPINE DERIVATIVES AS RSV INHIBITORS ENANTA PHARM INC (US) 2023-03-23 — — US disclosed
US-20220323460-A1 COMBINATION PHARMACEUTICAL AGENTS AS RSV INHIBITORS ENANTA PHARM INC (US) 2022-10-13 — — US disclosed
US-11390631-B1 Benzodiazepine derivatives as RSV inhibitors ENANTA PHARMACEUTICALS, INC. (US) 2022-07-19 — — US disclosed
EP-3324977-B1 BENZODIAZEPINE DERIVATIVES AS RSV INHIBITORS ENANTA PHARM INC (US) 2022-07-13 — — EP disclosed
CN-108200760-A BENZODIAZEPINE DERIVATIVES AS RSV INHIBITORS 英安塔制药有限公司 2018-06-22 — — CN disclosed
EP-3324977-A1 BENZODIAZEPINE DERIVATIVES AS RSV INHIBITORS Enanta Pharmaceuticals, Inc. (US) 2018-05-30 — — EP disclosed
US-9957281-B2 Benzodiazepine derivatives as RSV inhibitors ENANTA PHARMACEUTICALS, INC. (US) 2018-05-01 — — US disclosed
US-9957281-B2 Benzodiazepine derivatives as RSV inhibitors ENANTA PHARMACEUTICALS, INC. (US) 2018-05-01 — — US disclosed
US-20170022221-A1 BENZODIAZEPINE DERIVATIVES AS RSV INHIBITORS ENANTA PHARMACEUTICALS, INC. 2017-01-26 — — US disclosed
WO-2017015449-A1 BENZODIAZEPINE DERIVATIVES AS RSV INHIBITORS ENANTA PHARMACEUTICALS, INC. (US) 2017-01-26 — — WO disclosed
US-9365540-B2 Benzimidazole derivatives as MCH receptor antagonists TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2016-06-14 — — US disclosed
EP-2802571-A1 BENZIMIDAZOLE DERIVATIVES AS MCH RECEPTOR ANTAGONISTS Takeda Pharmaceutical Company Limited (JP) 2014-11-19 — — EP disclosed
WO-2013105676-A1 BENZIMIDAZOLE DERIVATIVES AS MCH RECEPTOR ANTAGONISTS TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2013-07-18 — — WO disclosed
US-5395845-A Insecticides ROUSSEL-UCLAF (FR) 1995-03-07 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240360155-A1 Benzodiazepine Derivatives as RSV Inhibitors GABRA5, GABRA1, GABBR2 RAB9A 1384/4885MAPT 2157/4885NPC1 224/4885
US-11952389-B2 Benzodiazepine derivatives as RSV inhibitors GABRA5, GABRA1, GABBR2 RAB9A 1384/4885MAPT 2157/4885NPC1 224/4885
US-11390631-B1 Benzodiazepine derivatives as RSV inhibitors GABRA5, GABRA1, GABBR2 RAB9A 1384/4885MAPT 2157/4885NPC1 224/4885
US-12297209-B2 Benzodiazepine derivatives as RSV inhibitors GABRA5, GABRA1, GABBR2 RAB9A 1384/4885MAPT 2157/4885NPC1 224/4885
US-20220323460-A1 COMBINATION PHARMACEUTICAL AGENTS AS RSV INHIBITORS SERPINB1, FURIN, HIF1AN RAB9A 704/4885MAPT 3417/4885NPC1 480/4885
US-20230087410-A1 BENZODIAZEPINE DERIVATIVES AS RSV INHIBITORS GABRA5, GABRA1, GABBR2 RAB9A 1384/4885MAPT 2157/4885NPC1 224/4885
US-12268694-B2 Combination pharmaceutical agents as RSV inhibitors ACE, ACE2, SPCS3 RAB9A 384/4885MAPT 2865/4885NPC1 399/4885
US-20170022221-A1 BENZODIAZEPINE DERIVATIVES AS RSV INHIBITORS GABRA5, GABRA1, GABBR2 RAB9A 1384/4885MAPT 2157/4885NPC1 224/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.