Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 5/20 | 0.49 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.39 |
| ▸ | AKT1 | P31749 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.35 |
| ▸ | TYK2 | P29597 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29532603 | 1.00 | TRPM8 (0.49) | TRPM8EPHX1P2RX4AKT1TRPV1 | |
| SCHEMBL23907960 | 0.93 | TRPM8 (0.41) | TRPM8EPHX1P2RX4AKT1TRPV1 | |
| SCHEMBL28586171 | 0.83 | TRPM8 (0.42) | TRPM8EPHX1TRPV1CYP19A1 | |
| SCHEMBL926043 | 0.77 | TRPM8 (0.57) | TRPM8EPHX1P2RX4TRPV1CYP19A1 | |
| SCHEMBL2628761 | 0.76 | TRPM8 (0.58) | TRPM8EPHX1P2RX4 | |
| SCHEMBL4812089 | 0.76 | P2RX4 (0.61) | TRPM8EPHX1P2RX4TRPV1 | |
| SCHEMBL2628773 | 0.76 | TRPM8 (0.58) | TRPM8EPHX1P2RX4TRPV1 | |
| SCHEMBL4820315 | 0.76 | TRPM8 (0.55) | TRPM8EPHX1P2RX4 | |
| SCHEMBL28586168 | 0.76 | TRPV1 (0.35) | TRPM8TRPV1CYP19A1 | |
| SCHEMBL2628771 | 0.75 | TRPM8 (0.57) | TRPM8EPHX1P2RX4TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 83 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3494104-B1 | WARMING SENSATION COMPOUNDS | TAKASAGO PERFUMERY CO LTD (JP) | 2023-11-15 | — | — | EP | claimed |
| EP-3996506-A1 | FORMULATIONS FOR CONTROL AND REPELLENCY OF BITING ARTHROPODS | Bedoukian Research, Inc. (US) | 2022-05-18 | — | — | EP | claimed |
| EP-3996505-A1 | SYNERGISTIC FORMULATIONS FOR CONTROL AND REPELLENCY OF BITING ARTHROPODS | Bedoukian Research, Inc. (US) | 2022-05-18 | — | — | EP | claimed |
| CN-109803948-B | Warming sensation compound | 高砂香料工业株式会社 | 2022-03-01 | — | — | CN | claimed |
| US-11059771-B2 | Warming sensation compounds | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2021-07-13 | — | — | US | claimed |
| US-11034644-B2 | — | — | 2021-06-15 | — | — | US | claimed |
| WO-2021071896-A1 | SYNERGISTIC FORMULATIONS FOR CONTROL AND REPELLENCY OF BITING ARTHROPODS | BEDOUKIAN RESEARCH, INC. (US) | 2021-04-15 | — | — | WO | claimed |
| WO-2021071898-A1 | FORMULATIONS FOR CONTROL AND REPELLENCY OF BITING ARTHROPODS | BEDOUKIAN RESEARCH, INC. (US) | 2021-04-15 | — | — | WO | claimed |
| US-20210100242-A1 | FORMULATIONS FOR CONTROL AND REPELLENCY OF BITING ARTHROPODS | BEDOUKIAN RESEARCH, INC. (US) | 2021-04-08 | — | — | US | claimed |
| US-20210100245-A1 | SYNERGISTIC FORMULATIONS FOR CONTROL AND REPELLENCY OF BITING ARTHROPODS | BEDOUKIAN RESEARCH, INC. (US) | 2021-04-08 | — | — | US | claimed |
| US-10392371-B2 | Compounds useful as modulators of TRPM8 | SENOMYX, INC. (US) | 2019-08-27 | — | — | US | claimed |
| EP-3494104-A1 | WARMING SENSATION COMPOUNDS | Takasago International Corporation (JP) | 2019-06-12 | — | — | EP | claimed |
| US-20190169111-A1 | WARMING SENSATION COMPOUNDS | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2019-06-06 | — | — | US | claimed |
| WO-2018027202-A1 | WARMING SENSATION COMPOUNDS | TAKASAGO INTERNATIONAL CORPORATION (USA) (US) | 2018-02-08 | — | — | WO | claimed |
| WO-2014198366-A1 | GLOVE WITH A COOLING EFFECT | CARL FREUDENBERG KG (DE) | 2014-12-18 | — | — | WO | claimed |
| CN-115279328-B | Structured rheological solid compositions | 宝洁公司 | 2024-07-05 | — | — | CN | disclosed |
| EP-3494104-B1 | WARMING SENSATION COMPOUNDS | TAKASAGO PERFUMERY CO LTD (JP) | 2023-11-15 | — | — | EP | disclosed |
| US-20080305051-A1 | Menthane Carboxamide Derivatives Having Cooling Properties | GIVAUDAN S.A. (CH) | 2008-12-11 | — | — | US | disclosed |
| EP-1853565-A1 | MENTHANE CARBOXAMIDE DERIVATIVES HAVING COOLING PROPERTIES | Givaudan SA (CH) | 2007-11-14 | — | — | EP | disclosed |
| WO-2006092074-A1 | MENTHANE CARBOXAMIDE DERIVATIVES HAVING COOLING PROPERTIES | GIVAUDAN SA (CH) | 2006-09-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210100242-A1 | FORMULATIONS FOR CONTROL AND REPELLENCY OF BITING ARTHROPODS | ACHE, NISCH, DDT | TRPM8 590/4885EPHX1 1147/4885P2RX4 2129/4885 |
| US-11059771-B2 | Warming sensation compounds | TRPA1, TRPV1, TRPV4 | TRPM8 6/4885EPHX1 1930/4885P2RX4 77/4885 |
| US-20210100245-A1 | SYNERGISTIC FORMULATIONS FOR CONTROL AND REPELLENCY OF BITING ARTHROPODS | NOTUM, SGMS1, COASY | TRPM8 1553/4885EPHX1 1562/4885P2RX4 3975/4885 |
| US-10392371-B2 | Compounds useful as modulators of TRPM8 | TRPM8, TRPM4, TRPM6 | TRPM8 1/4885EPHX1 4010/4885P2RX4 197/4885 |
| US-11034644-B2 | — | TRPA1, TRPV1, TRPV5 | TRPM8 7/4885EPHX1 1372/4885P2RX4 437/4885 |
| US-20190169111-A1 | WARMING SENSATION COMPOUNDS | TRPA1, TRPV1, TRPV4 | TRPM8 6/4885EPHX1 1930/4885P2RX4 77/4885 |
| US-20080305051-A1 | Menthane Carboxamide Derivatives Having Cooling Properties | MDH2, ME2, H1-0 | TRPM8 72/4885EPHX1 680/4885P2RX4 1277/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.