Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 10/20 | 0.81 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.67 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.65 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.65 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8610309 | 0.90 | PTGS2 (1.00) | PTGS2ALOX5PTGS1CYP2C9PDPK1 | |
| SCHEMBL8640401 | 0.89 | PTGS2 (0.82) | PTGS2PTGS1CYP2C9 | |
| SCHEMBL9003005 | 0.89 | PTGS2 (0.67) | PTGS2PTGS1CYP2C9PDPK1 | |
| SCHEMBL9003167 | 0.88 | PTGS2 (0.65) | PTGS2PTGS1CYP2C9 | |
| SCHEMBL9002935 | 0.88 | PTGS2 (0.82) | PTGS2ALOX5PTGS1CYP2C9PDPK1 | |
| SCHEMBL9257388 | 0.88 | PTGS2 (0.81) | PTGS2ALOX5PTGS1CYP2C9PDPK1 | |
| SCHEMBL9003059 | 0.85 | PTGS2 (0.78) | PTGS2ALOX5PTGS1CYP2C9PDPK1 | |
| SCHEMBL8765387 | 0.85 | PTGS2 (0.90) | PTGS2ALOX5PTGS1CYP2C9PDPK1 | |
| SCHEMBL17369546 | 0.80 | ALOX5 (1.00) | PTGS2ALOX5PTGS1CYP2C9 | |
| SCHEMBL6957077 | 0.80 | PTGS2 (0.80) | PTGS2ALOX5PTGS1CYP2C9PDPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5475018-A | Antiinflammatory agent, antiarthritic agent; analgesics and antipyretics | G. D. SEARLE & CO. (US) | 1995-12-12 | — | — | US | disclosed |