Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAT2A | P31153 | 2/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TSPO | P30536 | 1/20 | 0.35 |
| ▸ | PHGDH | O43175 | 2/20 | 0.35 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9261214 | 0.96 | ADORA2B (0.41) | HPGDADORA2BKDM4EMAT2AADORA1 | |
| SCHEMBL9257773 | 0.86 | ADORA2B (0.37) | HPGDADORA2BKDM4EADORA1MAPT | |
| SCHEMBL9257774 | 0.84 | ADORA3 (0.43) | ADORA2BKDM4EADORA1PDE4DALDH1A1 | |
| SCHEMBL9264420 | 0.83 | CXCR3 (0.39) | HPGDKDM4EADORA1MAPTALDH1A1 | |
| SCHEMBL9258312 | 0.81 | ADORA1 (0.38) | HPGDADORA2BKDM4EADORA1HTR2B | |
| SCHEMBL9265963 | 0.78 | TSPO (0.46) | HPGDKDM4EMAT2ATSPO | |
| SCHEMBL9262280 | 0.75 | KDM4E (0.46) | HPGDADORA2BKDM4EADORA1MAPT | |
| SCHEMBL9257923 | 0.74 | TSPO (0.46) | HPGDADORA2BKDM4EMAT2ATSPO | |
| SCHEMBL9261380 | 0.72 | MAPT (0.41) | ADORA2BKDM4EMAT2AADORA1MAPT | |
| SCHEMBL9416617 | 0.72 | ADORA1 (0.39) | HPGDADORA2BKDM4EADORA1HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5466706-A | Compounds for hypnotics, anxiety or anticonvulsants | SYNTHELABO (FR) | 1995-11-14 | — | — | US | disclosed |
| EP-0607076-A1 | 9H-Imidazo 1,2-a benzimidazole derivatives with GABA activity | SYNTHELABO (FR) | 1994-07-20 | — | — | EP | disclosed |