Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.58 |
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.47 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.43 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12051678 | 0.85 | ALDH1A1 (0.68) | ALDH1A1RECQLSMN1; SMN2L3MBTL1MEN1 | |
| SCHEMBL7785749 | 0.81 | CHRM3 (0.48) | ALDH1A1LMNAL3MBTL1MEN1KMT2A | |
| SCHEMBL7795981 | 0.80 | FABP4 (0.50) | ALDH1A1LMNAL3MBTL1MEN1KMT2A | |
| SCHEMBL9251204 | 0.78 | POLB (0.43) | ALDH1A1RECQLSMN1; SMN2LMNAMEN1 | |
| SCHEMBL7791770 | 0.76 | GHSR (0.47) | SMN1; SMN2 | |
| SCHEMBL14003501 | 0.75 | ALDH1A1 (1.00) | ALDH1A1RECQLSMN1; SMN2MEN1KMT2A | |
| SCHEMBL16919653 | 0.74 | ALDH1A1 (0.60) | ALDH1A1RECQLSMN1; SMN2MEN1KMT2A | |
| SCHEMBL5105758 | 0.74 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2LMNAL3MBTL1MEN1 | |
| SCHEMBL34420050 | 0.74 | CA12 (0.64) | ALDH1A1L3MBTL1MEN1KMT2AMAPT | |
| SCHEMBL7791555 | 0.74 | MTNR1A (0.55) | MAPTHDAC3HDAC1HDAC2HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995016675-A1 | BENZO-FUSED LACTAMS PROMOTE RELEASE OF GROWTH HORMONE | MERCK & CO., INC. (US) | 1995-06-22 | — | — | WO | disclosed |