Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 3/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAP2 | P11137 | 1/20 | 0.34 |
| ▸ | TSPO | P30536 | 1/20 | 0.34 |
| ▸ | MPO | P05164 | 1/20 | 0.34 |
| ▸ | XDH | P47989 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9269032 | 0.75 | CSF1R (0.42) | CNR1ADRA2AADRA2BADRA2CHTR7 | |
| SCHEMBL9270566 | 0.69 | PRNP (0.36) | — | |
| SCHEMBL9268657 | 0.68 | KCNH2 (0.41) | — | |
| SCHEMBL9270496 | 0.68 | MEN1 (0.37) | — | |
| SCHEMBL9270253 | 0.65 | ALDH1A1 (0.43) | PTGS2MAPT | |
| SCHEMBL9266252 | 0.63 | PTGS2 (0.35) | PTGS2MAPT | |
| SCHEMBL3306285 | 0.62 | POLB (0.56) | CNR1MAPT | |
| SCHEMBL6991966 | 0.62 | MEN1 (0.52) | ADRA2AADRA2BADRA2CHTR7HTR2B | |
| SCHEMBL28750582 | 0.61 | TSPO (0.56) | CNR1SIRT1TSPO | |
| SCHEMBL15873533 | 0.60 | ACHE (0.55) | HTR2BPTGS2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995024395-A1 | QUINOLINE DERIVATIVES AS IMMUNOMODULATORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-09-14 | — | — | WO | disclosed |