Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.65 |
| ▸ | NPC1 | O15118 | 3/20 | 0.65 |
| ▸ | POLB | P06746 | 2/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9275859 | 0.88 | RAB9A (0.62) | RAB9ANPC1POLBL3MBTL1SMN1; SMN2 | |
| SCHEMBL16866144 | 0.83 | NPC1 (0.86) | RAB9ANPC1POLBL3MBTL1SMN1; SMN2 | |
| SCHEMBL23573491 | 0.81 | NPC1 (0.77) | RAB9ANPC1POLBL3MBTL1SMN1; SMN2 | |
| SCHEMBL23573490 | 0.81 | NPC1 (0.77) | RAB9ANPC1POLBL3MBTL1SMN1; SMN2 | |
| SCHEMBL2750640 | 0.81 | RAB9A (0.97) | RAB9ANPC1POLBL3MBTL1SMN1; SMN2 | |
| SCHEMBL27267057 | 0.79 | RAB9A (1.00) | RAB9ANPC1POLBL3MBTL1SMN1; SMN2 | |
| SCHEMBL27264917 | 0.79 | RAB9A (1.00) | RAB9ANPC1POLBL3MBTL1SMN1; SMN2 | |
| SCHEMBL9270646 | 0.79 | RAB9A (0.67) | RAB9ANPC1SMN1; SMN2LMNAHTT | |
| SCHEMBL4983290 | 0.75 | L3MBTL1 (0.76) | RAB9ANPC1POLBL3MBTL1SMN1; SMN2 | |
| SCHEMBL9273863 | 0.74 | NPC1 (0.70) | RAB9ANPC1POLBL3MBTL1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5420164-A | Enzyme inhibitors | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1995-05-30 | — | — | US | disclosed |
| EP-0507291-A1 | Cyclohexylurea compounds | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1992-10-07 | — | — | EP | disclosed |