Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.67 |
| ▸ | UBE2M | P61081 | 1/20 | 0.55 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.51 |
| ▸ | MEN1 | O00255 | 5/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | NPY1R | P25929 | 1/20 | 0.51 |
| ▸ | NPY2R | P49146 | 1/20 | 0.51 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.50 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2751089 | 0.81 | RAB9A (1.00) | RAB9AUBE2MDCUN1D1HTTUSP30 | |
| SCHEMBL9269081 | 0.79 | RAB9A (0.65) | RAB9AHTTNPC1KMT2AMEN1 | |
| SCHEMBL9274428 | 0.77 | KMT2A (0.62) | RAB9AUBE2MDCUN1D1HTTNPC1 | |
| SCHEMBL9275859 | 0.77 | RAB9A (0.62) | RAB9AHTTNPC1KMT2AMEN1 | |
| SCHEMBL9271582 | 0.74 | MAPT (0.58) | KMT2AMEN1MAPTMAPK1LMNA | |
| SCHEMBL9270866 | 0.72 | NPC1 (0.62) | RAB9AUBE2MDCUN1D1HTTNPC1 | |
| SCHEMBL29022112 | 0.72 | RAB9A (0.85) | RAB9AHTTNPC1KMT2AMEN1 | |
| SCHEMBL21750894 | 0.71 | HTT (0.71) | RAB9AUBE2MDCUN1D1HTTUSP30 | |
| SCHEMBL1322743 | 0.71 | HTT (0.71) | RAB9AUBE2MDCUN1D1HTTUSP30 | |
| SCHEMBL29419622 | 0.71 | HTT (0.71) | RAB9AUBE2MDCUN1D1HTTUSP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5420164-A | Enzyme inhibitors | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1995-05-30 | — | — | US | disclosed |
| EP-0507291-A1 | Cyclohexylurea compounds | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1992-10-07 | — | — | EP | disclosed |