Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 7/20 | 0.43 |
| ▸ | CTSL | P07711 | 3/20 | 0.43 |
| ▸ | CTSS | P25774 | 3/20 | 0.43 |
| ▸ | CTSB | P07858 | 2/20 | 0.43 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.42 |
| ▸ | ACE | P12821 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | REN | P00797 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7285563 | 0.79 | SLC15A1 (0.42) | CTSKCTSLCTSSCTSBCAPN1 | |
| SCHEMBL3394167 | 0.76 | CTSK (0.56) | CTSKCTSLCTSSCTSB | |
| SCHEMBL3394165 | 0.76 | CTSK (0.56) | CTSKCTSLCTSSCTSB | |
| SCHEMBL30516234 | 0.76 | CTSK (0.56) | CTSKCTSLCTSSCTSB | |
| Hydrochloric Acid SCHEMBL11604468 | 0.75 | CTSK (0.55) | CTSKCTSLCTSSCTSB | |
| SCHEMBL27809385 | 0.73 | ANPEP (0.48) | CTSKCTSLCTSSCTSBCAPN1 | |
| SCHEMBL5934705 | 0.72 | CTSK (0.58) | CTSKCTSLCTSSCTSBCAPN1 | |
| SCHEMBL7480288 | 0.71 | MMP1 (0.53) | CTSKCTSLCTSSCTSBCAPN1 | |
| SCHEMBL14345793 | 0.71 | CTSC (0.55) | ACE | |
| SCHEMBL28034519 | 0.71 | CTSK (0.49) | CTSKCTSLCTSSCTSBCAPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0442754-B1 | Reagents and methods for stereospecific fluoromethylation | PROTOTEK INC (US) | 1995-12-27 | — | — | EP | disclosed |
| US-5344939-A | Esterification | PROTOTEK, INC. (US) | 1994-09-06 | — | — | US | disclosed |
| US-5210272-A | Using a magnesium fluoromalonate to fluoromethylate a carboxylic acid | PROTOTEK, INC. (US) | 1993-05-11 | — | — | US | disclosed |
| US-5101068-A | Monofluoromethylation of organic compounds, reaction with amino acids | PROTOTEK INC. (US) | 1992-03-31 | — | — | US | disclosed |
| EP-0442754-A2 | Reagents and methods for stereospecific fluoromethylation | PROTOTEK, INC., (US) | 1991-08-21 | — | — | EP | disclosed |