SCHEMBL7285563

SCHEMBL7285563

CC(C)CC(C(=O)CF)N(C(=O)OCc1ccccc1)C(=O)[C@@H](N)Cc1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
SLC15A1 P46059 2/20 0.42
ANPEP P15144 1/20 0.42
RNPEP Q9H4A4 1/20 0.42
DNPEP Q9ULA0 1/20 0.42
CTSB P07858 3/20 0.41
LTA4H P09960 1/20 0.40
CTSK P43235 3/20 0.39
CTSL P07711 2/20 0.39
CTSS P25774 2/20 0.39
ALDH1A1 P00352 1/20 0.38
ALPI P09923 1/20 0.38
PKM P14618 1/20 0.38
PTGS1 P23219 1/20 0.38
XIAP P98170 1/20 0.38
SLC7A5 Q01650 1/20 0.38
CAPN1 P07384 2/20 0.38
ABCB1 P08183 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10443784 0.89 SLC15A1 (0.46) SLC15A1ANPEPRNPEPDNPEPCTSB
SCHEMBL9193091 0.87 SLC15A1 (0.46) SLC15A1ANPEPRNPEPDNPEPLTA4H
SCHEMBL7301283 0.87 SLC15A1 (0.46) SLC15A1ANPEPRNPEPDNPEPLTA4H
SCHEMBL27809385 0.82 ANPEP (0.48) SLC15A1ANPEPRNPEPDNPEPCTSB
SCHEMBL7606122 0.81 CTSB (0.43) SLC15A1ANPEPRNPEPDNPEPCTSB
SCHEMBL28790921 0.81 SLC15A1 (0.50) SLC15A1LTA4HALDH1A1ALPIPKM
SCHEMBL11433447 0.80 SLC1A1 (0.41) SLC15A1ANPEPRNPEPDNPEPCTSB
SCHEMBL9274337 0.79 CTSK (0.43) CTSBCTSKCTSLCTSSCAPN1
SCHEMBL7275440 0.78 SLC15A1 (0.47) SLC15A1ANPEPRNPEPDNPEPCTSB
SCHEMBL5492848 0.78 LTA4H (0.50) ANPEPRNPEPDNPEPLTA4HALPI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0130679-A2 Alpha amino fluoro ketones ENZYME SYSTEMS PRODUCTS INC. (US) 1985-01-09 EP disclosed