SCHEMBL3261989

SCHEMBL3261989

CCCCCOc1ccc(C2C(=O)Oc3ccccc32)cc1

nearest known ligand 0.46

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.46
KCNA3 P22001 1/20 0.46
LTA4H P09960 2/20 0.46
GAA P10253 1/20 0.43
GPR174 Q9BXC1 1/20 0.41
NPC1 O15118 1/20 0.41
TP53 P04637 2/20 0.40
NR5A1 Q13285 1/20 0.40
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
CRBN Q96SW2 1/20 0.40
TSHR P16473 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL383949 0.88 KCNA3 (0.52) LMNAKCNA3LTA4HGAAGPR174
SCHEMBL29612322 0.87 MAPT (0.49) LMNALTA4HGAANPC1TP53
SCHEMBL5605404 0.84 ALDH1A1 (0.44) LMNAKCNA3GAAGPR174MEN1
SCHEMBL30561156 0.84 ALDH1A1 (0.44) LMNAKCNA3GAAGPR174MEN1
SCHEMBL824498 0.84 GAA (0.47) LMNALTA4HGAAGPR174
Nonane SCHEMBL27663344 0.84 GAA (0.56) GAAMEN1KMT2A
SCHEMBL13412705 0.82 NR5A1 (0.51) LMNALTA4HGAANPC1TP53
SCHEMBL3261982 0.82 LMNA (0.45) LMNAKCNA3GAATP53MEN1
SCHEMBL8705954 0.80 ESR1 (0.47) LTA4HGAANPC1NR5A1MEN1
SCHEMBL9280351 0.78 ALOX15 (0.49) LMNAGAAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3519489-A1 LOW EMISSIONS SCORCH INHIBITOR FOR POLYURETHANE FOAM Vanderbilt Chemicals, LLC (US) 2019-08-07 EP claimed
WO-2018064521-A1 LOW EMISSIONS SCORCH INHIBITOR FOR POLYURETHANE FOAM VANDERBILT CHEMICALS, LLC (US) 2018-04-05 WO claimed
US-20180094120-A1 LOW EMISSIONS SCORCH INHIBITOR FOR POLYURETHANE FOAM VANDERBILT CHEMICALS, LLC 2018-04-05 US claimed
US-10421851-B2 Low emissions scorch inhibitor for polyurethane foam VANDERBILT CHEMICALS, LLC 2019-09-24 US disclosed
EP-3519489-A1 LOW EMISSIONS SCORCH INHIBITOR FOR POLYURETHANE FOAM Vanderbilt Chemicals, LLC (US) 2019-08-07 EP disclosed
US-20180094120-A1 LOW EMISSIONS SCORCH INHIBITOR FOR POLYURETHANE FOAM VANDERBILT CHEMICALS, LLC 2018-04-05 US disclosed
WO-2018064521-A1 LOW EMISSIONS SCORCH INHIBITOR FOR POLYURETHANE FOAM VANDERBILT CHEMICALS, LLC (US) 2018-04-05 WO disclosed
US-8653284-B2 Lactone stabilizing compositions MILLIKEN & COMPANY (US) 2014-02-18 US disclosed
US-20100010124-A1 LACTONE STABILIZING COMPOSITIONS XIA JUSONG 2010-01-14 US disclosed
US-7601853-B2 Lactone stabilizing compositions MILLIKEN & COMPANY (US) 2009-10-13 US disclosed
EP-1824921-B1 LACTONE STABILIZING COMPOSITIONS MILLIKEN & CO (US) 2009-02-25 EP disclosed
US-20080217585-A1 LACTONE STABILIZING COMPOSITIONS XIA JUSONG 2008-09-11 US disclosed
US-7390912-B2 Lactone stabilizing compositions MILLIKEN & COMPANY (US) 2008-06-24 US disclosed
EP-1824921-A1 LACTONE STABILIZING COMPOSITIONS Milliken&Company (US) 2007-08-29 EP disclosed
US-20060135792-A1 Lactone stabilizing compositions MILLIKEN & COMPANY 2006-06-22 US disclosed
WO-2006065829-A1 LACTONE STABILIZING COMPOSITIONS MILLIKEN & COMPANY (US) 2006-06-22 WO disclosed
US-5488117-A FOR POLYMERS CIBA-GEIGY CORPORATION (US) 1996-01-30 US disclosed
US-5488117-A FOR POLYMERS CIBA-GEIGY CORPORATION (US) 1996-01-30 US disclosed
US-5369159-A Heat, oxidation and radiation resistance for polymers CIBA-GEIGY CORPORATION (US) 1994-11-29 US disclosed
US-5369159-A Heat, oxidation and radiation resistance for polymers CIBA-GEIGY CORPORATION (US) 1994-11-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080217585-A1 LACTONE STABILIZING COMPOSITIONS GLO1, LPO, CBR3 LMNA 411/4885KCNA3 1658/4885LTA4H 129/4885
US-20060135792-A1 Lactone stabilizing compositions GLO1, LPO, CBR3 LMNA 411/4885KCNA3 1658/4885LTA4H 129/4885
US-20100010124-A1 LACTONE STABILIZING COMPOSITIONS GLO1, LPO, CBR3 LMNA 411/4885KCNA3 1658/4885LTA4H 129/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.