Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 2/20 | 0.37 |
| ▸ | CNR2 | P34972 | 2/20 | 0.37 |
| ▸ | FAAH | O00519 | 2/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 4/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8551083 | 0.68 | MMP3 (0.44) | LMNABCHEACHEPDE10A | |
| SCHEMBL10083312 | 0.60 | MGAM (0.49) | CNR2LMNAHTTTSHRMGAM | |
| SCHEMBL28659625 | 0.59 | HTT (0.46) | CNR2LMNAACHEHTTMGAM | |
| SCHEMBL28089401 | 0.59 | HTT (0.37) | CNR2LMNAHTTMGAMPDE10A | |
| SCHEMBL2631079 | 0.59 | HRH3 (0.65) | HRH3HTTPDE10A | |
| SCHEMBL22127183 | 0.58 | NCF1 (0.47) | LMNAACHEHTTMGAM | |
| SCHEMBL28408101 | 0.58 | LMNA (0.39) | CNR2HRH3LMNAACHEHTT | |
| SCHEMBL4936198 | 0.58 | LMNA (0.39) | HRH3LMNAACHEHTTMGAM | |
| SCHEMBL28812734 | 0.58 | ALDH1A1 (0.46) | CNR1LMNAHTT | |
| Benzene SCHEMBL27625550 | 0.58 | MGAM (0.54) | CNR2LMNAACHEMGAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995031458-A1 | 3-HYDROXYQUINUCLIDIN-3-YLPHENYLQUINOLINES AS SQUALENE SYNTHASE INHIBITORS | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1995-11-23 | — | — | WO | disclosed |
| WO-1995031458-A1 | 3-HYDROXYQUINUCLIDIN-3-YLPHENYLQUINOLINES AS SQUALENE SYNTHASE INHIBITORS | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1995-11-23 | — | — | WO | disclosed |