Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.30 |
| ▸ | LOX | P28300 | 1/20 | 0.30 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL258494 | 0.76 | GABRA1 (0.46) | ALDH1A1SMN1; SMN2TSHRPOLBMAPT | |
| SCHEMBL3937091 | 0.76 | POLB (0.52) | ALDH1A1SMN1; SMN2TSHRPOLBMAPT | |
| SCHEMBL23838393 | 0.72 | HSPA5 (0.38) | ALDH1A1SMN1; SMN2MAPTGAACA2 | |
| SCHEMBL10920632 | 0.71 | POLB (0.44) | ALDH1A1SMN1; SMN2TSHRPOLBMAPT | |
| SCHEMBL2584981 | 0.70 | SHBG (0.37) | ALDH1A1POLBMAPTGAACA2 | |
| SCHEMBL8403864 | 0.70 | ALDH1A1 (0.46) | ALDH1A1TSHRPOLBMAPTGAA | |
| SCHEMBL561582 | 0.67 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2TSHRPOLBMAPT | |
| SCHEMBL3937543 | 0.67 | CA2 (0.38) | ALDH1A1SMN1; SMN2TSHRPOLBMAPT | |
| SCHEMBL4901587 | 0.67 | POLB (0.62) | ALDH1A1POLBMAPTGAACA2 | |
| SCHEMBL5157299 | 0.67 | POLB (0.62) | ALDH1A1POLBMAPTGAACA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5362822-A | Epoxy resin for polyurethane having enhanced mechanical properties | THE DOW CHEMICAL COMPANY (US) | 1994-11-08 | — | — | US | disclosed |
| US-5189117-A | Tensile strength, tear strength, waterproofing | THE DOW CHEMICAL COMPANY (US) | 1993-02-23 | — | — | US | disclosed |