Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | PTGES | O14684 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.33 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.32 |
| ▸ | POLQ | O75417 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9299307 | 0.84 | ALOX5 (0.41) | PTGESALOX5 | |
| SCHEMBL9299028 | 0.79 | PTGES (0.45) | PKMPTGESAKR1C3ALOX5FFAR1 | |
| SCHEMBL9299828 | 0.78 | ALOX5 (0.36) | ALOX5FFAR1 | |
| SCHEMBL9300259 | 0.76 | ACHE (0.39) | ALDH1A1MAPTHPGDHTTNPSR1 | |
| SCHEMBL9300560 | 0.76 | ALOX5 (0.44) | ALDH1A1MAPTPKMHPGDHTT | |
| SCHEMBL9300627 | 0.72 | ALOX5 (0.45) | PTGESALOX5 | |
| SCHEMBL9299972 | 0.70 | ALOX5 (0.40) | ALOX5FFAR1 | |
| SCHEMBL9299499 | 0.67 | PTGES (0.42) | PTGESALOX5PTGDR2 | |
| SCHEMBL9299660 | 0.67 | PTGES (0.45) | L3MBTL1PTGESALOX5FFAR1HSD17B2 | |
| SCHEMBL9299121 | 0.67 | ACACB (0.41) | ALDH1A1MAPTHPGDHTTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5326902-A | Oxyalkyne compounds, pharmaceutical compositions containing them and processes for preparing such compounds and compositions | GRUENENTHAL GMBH (DE) | 1994-07-05 | — | — | US | disclosed |