Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | LAP3 | P28838 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | XBP1 | P17861 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ACP3 | P15309 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | CA5A | P35218 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9300378 | 0.82 | LMNA (0.47) | LMNAPOLBMEN1KMT2ATSHR | |
| SCHEMBL9714149 | 0.79 | POLB (0.45) | LMNAPOLBMEN1KMT2ATSHR | |
| SCHEMBL2856835 | 0.79 | LMNA (0.48) | LMNAPOLBMEN1KMT2ATSHR | |
| SCHEMBL788438 | 0.78 | LMNA (0.52) | LMNAPOLBMEN1KMT2ATSHR | |
| SCHEMBL10040040 | 0.77 | TSHR (0.41) | LMNAPOLBTSHRKDM4ETDP1 | |
| SCHEMBL95085 | 0.76 | L3MBTL1 (0.48) | LMNAPOLBTSHRTDP1SRC | |
| SCHEMBL21352327 | 0.76 | CA2 (0.44) | LMNAPOLBTSHRTDP1SRC | |
| SCHEMBL27884622 | 0.76 | LMNA (0.50) | LMNAPOLBMEN1KMT2ATSHR | |
| SCHEMBL11310454 | 0.74 | KDM4E (0.42) | LMNAPOLBMEN1KMT2ATSHR | |
| SCHEMBL14681161 | 0.74 | TSHR (0.42) | LMNAPOLBMEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5310808-A | Flame-retardant thermoplastic copolymers based on vinyl phosphonate derivatives grafted onto rubber | ARCO CHEMICAL TECHNOLOGY, L.P. (US) | 1994-05-10 | — | — | US | disclosed |
| US-5292817-A | Flame-retardant thermoplastic copolymers based on vinyl phosphonate derivatives grafted onto rubber | ARCO CHEMICAL TECHNOLOGY, L.P. (US) | 1994-03-08 | — | — | US | disclosed |