Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9301644 | 0.77 | S100A4 (0.48) | CCR1MAOB | |
| SCHEMBL9301241 | 0.75 | USP8 (0.41) | MAOB | |
| SCHEMBL9301263 | 0.75 | CCR1 (0.33) | CCR1MAOB | |
| SCHEMBL9302208 | 0.73 | TDP1 (0.55) | — | |
| SCHEMBL9684483 | 0.71 | ALDH1A1 (0.35) | NPC1RAB9AMAOB | |
| SCHEMBL9685915 | 0.70 | ALDH1A1 (0.37) | RAB9AMAOB | |
| SCHEMBL29117498 | 0.70 | ELANE (0.55) | NPC1RAB9AMAOBATM | |
| SCHEMBL9849269 | 0.69 | ELANE (0.53) | NPC1RAB9AATM | |
| SCHEMBL9302015 | 0.67 | GAA (0.55) | — | |
| SCHEMBL9301675 | 0.64 | TDP1 (0.55) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994009002-A1 | 2-(AZA-9-FLUORENONYL)CARBAPENEM ANTIBACTERIAL AGENTS | MERCK & CO., INC. (US) | 1994-04-28 | — | — | WO | disclosed |
| US-5294610-A | Staphylococcus; side effect reduction | MERCK & CO. INC. (US) | 1994-03-15 | — | — | US | disclosed |