Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9304073 | 0.84 | MAPT (0.39) | MAPTALDH1A1KDM4EHSD17B10POLB | |
| SCHEMBL9301938 | 0.83 | DRD3 (0.43) | ALDH1A1KDM4EPOLBGAAHPGD | |
| SCHEMBL9302904 | 0.81 | ALDH1A1 (0.45) | MAPTALDH1A1KDM4EHSD17B10POLB | |
| SCHEMBL22724875 | 0.75 | ALDH1A1 (0.48) | MAPTALDH1A1KDM4EHSD17B10POLB | |
| SCHEMBL21937028 | 0.72 | MAPT (0.51) | MAPTALDH1A1KDM4EHSD17B10POLB | |
| Potassium SCHEMBL9744154 | 0.72 | HSD17B10 (0.45) | MAPTALDH1A1KDM4EHSD17B10POLB | |
| SCHEMBL9744143 | 0.72 | HSD17B10 (0.45) | MAPTALDH1A1KDM4EHSD17B10POLB | |
| Potassium Ion SCHEMBL9744147 | 0.71 | ALDH1A1 (0.42) | MAPTALDH1A1KDM4EHSD17B10POLB | |
| SCHEMBL24125575 | 0.69 | MAPT (0.47) | MAPTALDH1A1KDM4EHSD17B10POLB | |
| SCHEMBL9302880 | 0.69 | HTT (0.46) | MAPTALDH1A1KDM4EHSD17B10POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5283248-A | Bactericides, enzyme inhibitor of DNA-gyrase in bacteria | HOFFMANN-LA ROCHE INC. (US) | 1994-02-01 | — | — | US | disclosed |