Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | TNF | P01375 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | AR | P10275 | 4/20 | 0.48 |
| ▸ | GALR3 | O60755 | 2/20 | 0.46 |
| ▸ | NR2F2 | P24468 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | PTAFR | P25105 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | RORC | P51449 | 1/20 | 0.44 |
| ▸ | PGR | P06401 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9303506 | 0.84 | GALR3 (0.58) | ALDH1A1TNFMAPTTP53GALR3 | |
| SCHEMBL9302421 | 0.81 | ITGA1 (0.53) | ALDH1A1TNFMAPTGALR3NR2F2 | |
| SCHEMBL9302400 | 0.79 | ALDH1A1 (0.53) | ALDH1A1TNFMAPTTP53GALR3 | |
| SCHEMBL8752429 | 0.79 | AR (0.75) | ALDH1A1MAPTARLMNASMN1; SMN2 | |
| SCHEMBL9302427 | 0.77 | ALDH1A1 (0.53) | ALDH1A1TNFMAPTGALR3NR2F2 | |
| SCHEMBL9298869 | 0.74 | TNF (0.61) | ALDH1A1TNFGALR3NR2F2RAB9A | |
| SCHEMBL9298879 | 0.74 | TNF (0.57) | ALDH1A1TNFTP53GALR3NR2F2 | |
| SCHEMBL1160015 | 0.73 | BCL2L1 (0.53) | HDAC1HDAC6RORC | |
| SCHEMBL9301970 | 0.73 | GALR3 (0.57) | ALDH1A1TNFTP53GALR3NR2F2 | |
| SCHEMBL9299568 | 0.73 | TNF (0.54) | ALDH1A1TNFGALR3NR2F2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1990009997-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1990-09-07 | — | — | WO | claimed |
| US-5314880-A | Platelet activating factor antagonist | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1994-05-24 | — | — | US | disclosed |
| EP-0468971-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1992-02-05 | — | — | EP | disclosed |
| WO-1990009997-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1990-09-07 | — | — | WO | disclosed |