Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GALR3 | O60755 | 2/20 | 0.58 |
| ▸ | NR2F2 | P24468 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | TNF | P01375 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | PTAFR | P25105 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | EDNRA | P25101 | 1/20 | 0.47 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9302421 | 0.85 | ITGA1 (0.53) | GALR3NR2F2RAB9AALDH1A1TNF | |
| SCHEMBL9301970 | 0.84 | GALR3 (0.57) | GALR3NR2F2RAB9AALDH1A1TNF | |
| SCHEMBL9302369 | 0.84 | ALDH1A1 (0.52) | GALR3NR2F2RAB9AALDH1A1TNF | |
| SCHEMBL9302400 | 0.83 | ALDH1A1 (0.53) | GALR3NR2F2RAB9AALDH1A1TNF | |
| SCHEMBL9302427 | 0.81 | ALDH1A1 (0.53) | GALR3NR2F2RAB9AALDH1A1TNF | |
| SCHEMBL9304259 | 0.80 | GALR3 (0.69) | GALR3NR2F2RAB9AALDH1A1TNF | |
| SCHEMBL9303024 | 0.78 | PTAFR (0.58) | GALR3NR2F2RAB9ATNFHDAC1 | |
| SCHEMBL9298879 | 0.77 | TNF (0.57) | GALR3NR2F2RAB9AALDH1A1TNF | |
| SCHEMBL9300543 | 0.76 | TNF (0.67) | GALR3NR2F2RAB9AALDH1A1TNF | |
| SCHEMBL9302805 | 0.76 | TNF (0.53) | GALR3NR2F2RAB9AALDH1A1TNF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0468971-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1992-02-05 | — | — | EP | claimed |
| WO-1990009997-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1990-09-07 | — | — | WO | claimed |
| US-5314880-A | Platelet activating factor antagonist | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1994-05-24 | — | — | US | disclosed |
| EP-0468971-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1992-02-05 | — | — | EP | disclosed |
| WO-1990009997-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1990-09-07 | — | — | WO | disclosed |