Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | PTAFR | P25105 | 2/20 | 0.50 |
| ▸ | NR2F2 | P24468 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | GALR3 | O60755 | 2/20 | 0.49 |
| ▸ | TNF | P01375 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9302427 | 0.90 | ALDH1A1 (0.53) | ALDH1A1CYP2C19LMNAMAPTSMN1; SMN2 | |
| SCHEMBL9303635 | 0.86 | LMNA (0.59) | ALDH1A1TSHRMAPK1CYP2C19LMNA | |
| SCHEMBL9502580 | 0.85 | HTT (0.62) | ALDH1A1TSHRMAPK1CYP2C19LMNA | |
| SCHEMBL9303506 | 0.83 | GALR3 (0.58) | ALDH1A1MAPK1LMNATP53MAPT | |
| SCHEMBL9302369 | 0.79 | ALDH1A1 (0.52) | ALDH1A1CYP2C19LMNATP53MAPT | |
| SCHEMBL9302421 | 0.79 | ITGA1 (0.53) | ALDH1A1MAPTPTAFRNR2F2RAB9A | |
| SCHEMBL8129105 | 0.76 | HDAC1 (0.56) | ALDH1A1CYP2C19SMN1; SMN2HTTCYP1A2 | |
| SCHEMBL9299653 | 0.75 | TNF (0.59) | ALDH1A1CYP2C19TP53CYP1A2CYP2C9 | |
| SCHEMBL9298879 | 0.74 | TNF (0.57) | ALDH1A1CYP2C19TP53HTTCYP1A2 | |
| SCHEMBL8131553 | 0.74 | HDAC1 (0.54) | ALDH1A1CYP2C19LMNASMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0468971-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1992-02-05 | — | — | EP | claimed |
| WO-1990009997-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1990-09-07 | — | — | WO | claimed |
| US-5314880-A | Platelet activating factor antagonist | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1994-05-24 | — | — | US | disclosed |
| EP-0468971-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1992-02-05 | — | — | EP | disclosed |
| WO-1990009997-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1990-09-07 | — | — | WO | disclosed |