Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | GALR3 | O60755 | 2/20 | 0.49 |
| ▸ | NR2F2 | P24468 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | TNF | P01375 | 1/20 | 0.49 |
| ▸ | PTAFR | P25105 | 2/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.47 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ALDH3A1 | P30838 | 2/20 | 0.45 |
| ▸ | EDNRA | P25101 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9302400 | 0.90 | ALDH1A1 (0.53) | ALDH1A1GALR3NR2F2RAB9ATNF | |
| SCHEMBL9303506 | 0.81 | GALR3 (0.58) | ALDH1A1GALR3NR2F2RAB9ATNF | |
| SCHEMBL20422008 | 0.81 | TNF (0.62) | ALDH1A1GALR3NR2F2RAB9ATNF | |
| SCHEMBL9303635 | 0.80 | LMNA (0.59) | ALDH1A1GALR3NR2F2RAB9ATNF | |
| SCHEMBL9502580 | 0.79 | HTT (0.62) | ALDH1A1MEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL9302369 | 0.77 | ALDH1A1 (0.52) | ALDH1A1GALR3NR2F2RAB9ATNF | |
| SCHEMBL9302421 | 0.77 | ITGA1 (0.53) | ALDH1A1GALR3NR2F2RAB9ATNF | |
| SCHEMBL8129105 | 0.76 | HDAC1 (0.56) | ALDH1A1GALR3NR2F2RAB9ATNF | |
| SCHEMBL9298879 | 0.74 | TNF (0.57) | ALDH1A1GALR3NR2F2RAB9ATNF | |
| SCHEMBL8131553 | 0.74 | HDAC1 (0.54) | ALDH1A1GALR3NR2F2RAB9ATNF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1990009997-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1990-09-07 | — | — | WO | claimed |
| US-5314880-A | Platelet activating factor antagonist | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1994-05-24 | — | — | US | disclosed |
| EP-0468971-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1992-02-05 | — | — | EP | disclosed |
| WO-1990009997-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1990-09-07 | — | — | WO | disclosed |