Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 9/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ADRA1D | P25100 | 8/20 | 0.42 |
| ▸ | ADRA1B | P35368 | 8/20 | 0.42 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.40 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.39 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9302556 | 0.77 | ADRA1D (0.65) | ADRA1AADRA1DADRA1B | |
| SCHEMBL6097642 | 0.76 | ADRA1A (0.45) | ADRA1ATP53CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL9302459 | 0.74 | CXCR4 (0.54) | ADRA1ATP53CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL9301885 | 0.73 | CXCR4 (0.56) | ADRA1ATP53CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL9302550 | 0.71 | ADRA1A (0.53) | ADRA1ATP53CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL11638248 | 0.71 | ADRA1A (0.44) | ADRA1ATP53CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL9301904 | 0.70 | ADRA1A (0.51) | ADRA1ATP53CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL14367858 | 0.66 | ADRA1A (0.51) | ADRA1ATP53CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL11222841 | 0.66 | ADRA1A (0.43) | ADRA1ATP53CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL14367876 | 0.66 | ADRA1A (0.51) | ADRA1ATP53CYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5286735-A | Antidepressants, anxiolytic agents | PIERRE FABRE MEDICAMENT (FR) | 1994-02-15 | — | — | US | claimed |
| US-5286735-A | Antidepressants, anxiolytic agents | PIERRE FABRE MEDICAMENT (FR) | 1994-02-15 | — | — | US | disclosed |