Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 3/20 | 0.51 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.51 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.51 |
| ▸ | MGLL | Q99685 | 3/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.47 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.46 |
| ▸ | UBE2M | P61081 | 1/20 | 0.45 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9302364 | 0.88 | EPHX2 (0.46) | ADRA1AMGLLTP53CYP1A2CYP3A4 | |
| SCHEMBL9302190 | 0.87 | MGLL (0.45) | ADRA1AADRA1DADRA1BMGLLCYP2D6 | |
| SCHEMBL9301424 | 0.87 | ADRA1A (0.45) | ADRA1AADRA1DADRA1BTP53CYP1A2 | |
| SCHEMBL9302550 | 0.82 | ADRA1A (0.53) | ADRA1AADRA1DADRA1BTP53CYP1A2 | |
| SCHEMBL9301890 | 0.78 | L3MBTL1 (0.46) | MGLLTSHRL3MBTL1HSD11B1UBE2M | |
| SCHEMBL9302076 | 0.72 | EPHX2 (0.48) | ADRA1AADRA1DADRA1BMGLLKMT2A | |
| SCHEMBL9302313 | 0.72 | ADRA1D (0.57) | ADRA1AADRA1DADRA1BALDH1A1 | |
| SCHEMBL9302003 | 0.72 | ADRA1D (0.60) | ADRA1AADRA1DADRA1BMGLLTSHR | |
| SCHEMBL17715576 | 0.72 | L3MBTL1 (0.62) | MGLLL3MBTL1KMT2AMEN1HSD11B1 | |
| SCHEMBL9301885 | 0.72 | CXCR4 (0.56) | ADRA1ATP53CYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5286735-A | Antidepressants, anxiolytic agents | PIERRE FABRE MEDICAMENT (FR) | 1994-02-15 | — | — | US | claimed |
| US-5286735-A | Antidepressants, anxiolytic agents | PIERRE FABRE MEDICAMENT (FR) | 1994-02-15 | — | — | US | disclosed |