Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 10/20 | 0.65 |
| ▸ | ADRA1A | P35348 | 10/20 | 0.65 |
| ▸ | ADRA1B | P35368 | 10/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.57 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13493621 | 0.83 | ADRA1D (0.65) | ADRA1DADRA1AADRA1BALDH1A1HPGD | |
| SCHEMBL17484523 | 0.82 | HTR1A (0.53) | ADRA1DADRA1AADRA1BALDH1A1HPGD | |
| SCHEMBL7471573 | 0.79 | ADRA1D (1.00) | ADRA1DADRA1AADRA1BALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL8124825 | 0.78 | ADRA1D (0.98) | ADRA1DADRA1AADRA1BALDH1A1HPGD | |
| SCHEMBL9302494 | 0.77 | ADRA1A (0.49) | ADRA1DADRA1AADRA1B | |
| SCHEMBL7473727 | 0.77 | ADRA1D (1.00) | ADRA1DADRA1AADRA1BALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL8131921 | 0.76 | ADRA1D (0.98) | ADRA1DADRA1AADRA1BALDH1A1HPGD | |
| SCHEMBL18358970 | 0.76 | POLB (0.75) | ADRA1DADRA1AADRA1BALDH1A1HPGD | |
| SCHEMBL8367125 | 0.76 | POLB (0.75) | ADRA1DADRA1AADRA1BALDH1A1HPGD | |
| SCHEMBL9695874 | 0.76 | MTNR1A (0.65) | ADRA1AALDH1A1HPGDPOLBESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5286735-A | Antidepressants, anxiolytic agents | PIERRE FABRE MEDICAMENT (FR) | 1994-02-15 | — | — | US | claimed |
| US-5286735-A | Antidepressants, anxiolytic agents | PIERRE FABRE MEDICAMENT (FR) | 1994-02-15 | — | — | US | disclosed |