Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR4 | P61073 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | HTT | P42858 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 4/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.45 |
| ▸ | AIMP2 | Q13155 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.43 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.43 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9301885 | 0.89 | CXCR4 (0.56) | CXCR4MAPTHTTTP53MAPK1 | |
| SCHEMBL9302550 | 0.87 | ADRA1A (0.53) | MAPTKDM4EALDH1A1TP53SIGMAR1 | |
| SCHEMBL9302823 | 0.84 | ADRA1D (0.62) | CXCR4MAPTHTTKDM4EALDH1A1 | |
| SCHEMBL9302190 | 0.81 | MGLL (0.45) | ADRA1AADRA1DADRA1BCYP2D6CYP2C19 | |
| SCHEMBL9302452 | 0.76 | KDM4E (0.44) | CXCR4MAPTHTTKDM4EALDH1A1 | |
| SCHEMBL9302494 | 0.74 | ADRA1A (0.49) | TP53ADRA1AADRA1DADRA1BCYP1A2 | |
| SCHEMBL9301424 | 0.73 | ADRA1A (0.45) | GAATP53SMN1; SMN2ADRA1AADRA1D | |
| SCHEMBL9302364 | 0.72 | EPHX2 (0.46) | ALDH1A1TP53ADRA1ACYP1A2CYP3A4 | |
| SCHEMBL9303150 | 0.72 | ADRA1D (0.59) | CXCR4ALDH1A1SIGMAR1ADRA1AADRA1D | |
| SCHEMBL9301904 | 0.70 | ADRA1A (0.51) | KDM4EALDH1A1L3MBTL1TP53ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5286735-A | Antidepressants, anxiolytic agents | PIERRE FABRE MEDICAMENT (FR) | 1994-02-15 | — | — | US | claimed |
| US-5286735-A | Antidepressants, anxiolytic agents | PIERRE FABRE MEDICAMENT (FR) | 1994-02-15 | — | — | US | disclosed |