Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | KCNA3 | P22001 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | ICMT | O60725 | 2/20 | 0.33 |
| ▸ | TACR1 | P25103 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9303403 | 0.77 | SLC6A2 (0.43) | CYP2D6SLC6A4BACE1ICMTMEN1 | |
| SCHEMBL9302750 | 0.75 | DDB1 (0.37) | LMNASLC6A4BACE1ALDH1A1TACR1 | |
| SCHEMBL9304790 | 0.73 | TAAR1 (0.36) | SLC6A4BACE1TACR1TAAR1OPRM1 | |
| SCHEMBL9467170 | 0.73 | TSHR (0.47) | LMNASLC6A4BACE1MEN1CYP1A2 | |
| Formic Acid SCHEMBL9303273 | 0.71 | SLC6A2 (0.40) | CYP2D6KCNA3SLC6A4BACE1ICMT | |
| SCHEMBL9303673 | 0.70 | CNR2 (0.34) | TACR1TAAR1OPRM1OPRL1 | |
| SCHEMBL9304060 | 0.69 | KDM4E (0.36) | SLC6A4TACR1OPRM1OPRL1 | |
| SCHEMBL9304467 | 0.69 | UTS2R (0.35) | — | |
| SCHEMBL9304202 | 0.66 | SIGMAR1 (0.46) | MAOB | |
| SCHEMBL9869620 | 0.65 | SIGMAR1 (0.49) | SLC6A4TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0505379-B1 | MUSCARINIC RECEPTOR ANTAGONISTS | PFIZER LTD (GB) | 1994-07-20 | — | — | EP | disclosed |
| US-5300516-A | Muscarinic receptor antagonists | PFIZER INC. (US) | 1994-04-05 | — | — | US | disclosed |
| WO-1991009014-A1 | MUSCARINIC RECEPTOR ANTAGONISTS | PFIZER LIMITED (GB) | 1991-06-27 | — | — | WO | disclosed |