Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 9/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.34 |
| ▸ | ESRRG | P62508 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 2/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
| ▸ | FDPS | P14324 | 1/20 | 0.31 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.31 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.31 |
| ▸ | TACR1 | P25103 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9304790 | 0.92 | TAAR1 (0.36) | OPRM1OPRL1FDPSTACR1SLC6A4 | |
| SCHEMBL9303673 | 0.90 | CNR2 (0.34) | OPRM1OPRL1TACR1 | |
| SCHEMBL9304467 | 0.89 | UTS2R (0.35) | — | |
| SCHEMBL9302750 | 0.81 | DDB1 (0.37) | OPRM1OPRL1TACR1SLC6A4 | |
| SCHEMBL9869620 | 0.72 | SIGMAR1 (0.49) | FDPSSLC6A4 | |
| SCHEMBL9304044 | 0.71 | SIGMAR1 (0.42) | SLC6A4 | |
| SCHEMBL9303006 | 0.69 | LMNA (0.37) | OPRM1OPRL1TACR1SLC6A4 | |
| SCHEMBL9304202 | 0.66 | SIGMAR1 (0.46) | — | |
| SCHEMBL9303707 | 0.66 | SCN1A (0.38) | SLC6A4 | |
| SCHEMBL9467170 | 0.63 | TSHR (0.47) | KDM4EOPRM1OPRL1SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0505379-B1 | MUSCARINIC RECEPTOR ANTAGONISTS | PFIZER LTD (GB) | 1994-07-20 | — | — | EP | disclosed |
| US-5300516-A | Muscarinic receptor antagonists | PFIZER INC. (US) | 1994-04-05 | — | — | US | disclosed |