Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 1/20 | 0.37 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | TACR1 | P25103 | 2/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9304790 | 0.88 | TAAR1 (0.36) | DDB1CRBNOPRM1OPRL1TACR1 | |
| SCHEMBL9303673 | 0.82 | CNR2 (0.34) | OPRM1OPRL1TACR1 | |
| SCHEMBL9304467 | 0.81 | UTS2R (0.35) | — | |
| SCHEMBL9304060 | 0.81 | KDM4E (0.36) | OPRM1OPRL1TACR1SLC6A4 | |
| SCHEMBL9304202 | 0.77 | SIGMAR1 (0.46) | — | |
| SCHEMBL9303006 | 0.75 | LMNA (0.37) | OPRM1OPRL1ALDH1A1POLBHTR2C | |
| SCHEMBL9869620 | 0.71 | SIGMAR1 (0.49) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL9467170 | 0.68 | TSHR (0.47) | OPRM1OPRL1POLBTSHRSLC6A4 | |
| SCHEMBL9303465 | 0.67 | TSHR (0.47) | ALDH1A1RIPK1TSHRLMNA | |
| SCHEMBL9303864 | 0.67 | TSHR (0.47) | ALDH1A1RIPK1TSHRSLC6A4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0505379-B1 | MUSCARINIC RECEPTOR ANTAGONISTS | PFIZER LTD (GB) | 1994-07-20 | — | — | EP | disclosed |
| US-5300516-A | Muscarinic receptor antagonists | PFIZER INC. (US) | 1994-04-05 | — | — | US | disclosed |