Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | RORC | P51449 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.40 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | TLR9 | Q9NR96 | 4/20 | 0.39 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | STS | P08842 | 1/20 | 0.39 |
| ▸ | YAP1 | P46937 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9301969 | 0.91 | GRM5 (0.42) | RORCOPRM1OPRD1OGFRL1GRM5 | |
| SCHEMBL9302144 | 0.89 | GRM5 (0.39) | OPRM1OPRD1OGFRL1GRM5LMNA | |
| SCHEMBL9301682 | 0.87 | RORC (0.42) | RORCOPRM1OPRD1OGFRL1GPR119 | |
| SCHEMBL9303809 | 0.87 | HTT (0.41) | ACHERORCOPRM1OPRD1OGFRL1 | |
| SCHEMBL9301471 | 0.85 | RORC (0.41) | RORCOPRM1OPRD1OGFRL1GPR119 | |
| SCHEMBL9847732 | 0.85 | HTT (0.43) | ACHERORCOPRM1OPRD1OGFRL1 | |
| SCHEMBL9303690 | 0.85 | OPRM1 (0.37) | RORCOPRM1OPRD1OGFRL1 | |
| SCHEMBL9301681 | 0.84 | HTT (0.42) | RORCOPRM1OPRD1OGFRL1GPR119 | |
| SCHEMBL9302442 | 0.84 | RORC (0.41) | RORCOPRM1OPRD1OGFRL1TLR9 | |
| SCHEMBL9301575 | 0.82 | RORC (0.39) | ACHERORCOPRM1OPRD1OGFRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5283248-A | Bactericides, enzyme inhibitor of DNA-gyrase in bacteria | HOFFMANN-LA ROCHE INC. (US) | 1994-02-01 | — | — | US | disclosed |