Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 1/20 | 0.52 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.48 |
| ▸ | PLAU | P00749 | 5/20 | 0.45 |
| ▸ | F2 | P00734 | 2/20 | 0.45 |
| ▸ | PLG | P00747 | 2/20 | 0.45 |
| ▸ | PLAT | P00750 | 2/20 | 0.45 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.45 |
| ▸ | PLK4 | O00444 | 1/20 | 0.44 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.44 |
| ▸ | AURKA | O14965 | 1/20 | 0.44 |
| ▸ | CHUK | O15111 | 1/20 | 0.44 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.44 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.44 |
| ▸ | PAK4 | O96013 | 1/20 | 0.44 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.44 |
| ▸ | CDK1 | P06493 | 1/20 | 0.44 |
| ▸ | PIM1 | P11309 | 1/20 | 0.44 |
| ▸ | PRKACA | P17612 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9303131 | 0.88 | SIRT2 (0.46) | SIRT2PLAUF2PLGPLAT | |
| SCHEMBL9304048 | 0.87 | SIRT2 (0.55) | PTGESSIRT2PLAUF2PLG | |
| SCHEMBL9303308 | 0.84 | PTGES (0.56) | PTGESSIRT2PLK4CHEK1AURKA | |
| SCHEMBL9304320 | 0.84 | PLAU (0.50) | PTGESSIRT2PLAUF2PLG | |
| SCHEMBL9304321 | 0.81 | PLAU (0.50) | PTGESSIRT2PLAUF2PLG | |
| SCHEMBL9302810 | 0.81 | NPC1 (0.49) | MEN1KMT2ARXFP1NPC1RAB9A | |
| SCHEMBL9303249 | 0.81 | PLAU (0.60) | PTGESPLAUF2PLGPLAT | |
| SCHEMBL9303301 | 0.81 | PTGES (0.49) | PTGESSIRT2PLAUF2PLG | |
| SCHEMBL9305495 | 0.80 | PLAU (0.54) | PTGESPLAUF2PLGPLAT | |
| SCHEMBL9303041 | 0.79 | PLAU (0.61) | PLAUF2PLGPLATKLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5352704-A | Antiviral agents | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1994-10-04 | — | — | US | disclosed |
| EP-0434432-B1 | Guanidinobenzene derivatives | BANYU PHARMA CO LTD (JP) | 1994-05-04 | — | — | EP | disclosed |
| EP-0434432-A1 | Guanidinobenzene derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1991-06-26 | — | — | EP | disclosed |