Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 7/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 3/20 | 0.33 |
| ▸ | MIF | P14174 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 3/20 | 0.32 |
| ▸ | ACHE | P22303 | 3/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD5 | P21918 | 1/20 | 0.32 |
| ▸ | HTR7 | P34969 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.32 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9302379 | 0.96 | MAOB (0.36) | MAOBTSHRKDM4EUSP2ALDH1A1 | |
| SCHEMBL8980658 | 0.91 | PKM (0.37) | MAOBTSHRALDH1A1PKMMAOA | |
| SCHEMBL7386417 | 0.80 | ALDH1A1 (0.46) | TSHRKDM4EALDH1A1MIF | |
| SCHEMBL9304172 | 0.80 | KDM4E (0.34) | MAOBTSHRKDM4EUSP2ALDH1A1 | |
| SCHEMBL9165703 | 0.80 | PTGS2 (0.35) | MAOBBCHEACHEHTR7 | |
| SCHEMBL8981116 | 0.80 | RXFP1 (0.39) | MAOBTSHRALDH1A1LMNA | |
| SCHEMBL9809777 | 0.79 | MAOB (0.40) | MAOBKDM4EALDH1A1BCHEACHE | |
| SCHEMBL13063351 | 0.78 | PKM (0.38) | TSHRPKMBCHEDRD2DRD5 | |
| SCHEMBL8980569 | 0.77 | TDP1 (0.41) | TSHRKDM4EALDH1A1LMNAPKM | |
| SCHEMBL9173037 | 0.77 | HTR7 (0.37) | TSHRPKMDRD2DRD5HTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5308844-A | ANTIDEPRESSANT, ANXIOLYTIC AGENT, ANALGESIC, HYPOTENSIVE AGENT | PIERRE FABRE MEDICAMENT (FR) | 1994-05-03 | — | — | US | disclosed |