Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPE | Q05469 | 5/20 | 0.43 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.43 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.43 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.43 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 6/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9389676 | 0.90 | AURKA (0.41) | — | |
| SCHEMBL9303626 | 0.83 | PLAAT3 (0.48) | LIPEPLAAT3PLAAT5PLAAT2PLAAT4 | |
| SCHEMBL9382944 | 0.81 | RAB9A (0.36) | MAPK1LMNARAB9ATSHRSMN1; SMN2 | |
| SCHEMBL8547249 | 0.81 | AURKA (0.45) | LMNARAB9ATSHRSMN1; SMN2 | |
| SCHEMBL9388070 | 0.81 | L3MBTL1 (0.36) | MAPK1SCN9AMAPTNPSR1LMNA | |
| SCHEMBL9469206 | 0.80 | AURKA (0.42) | SCN9ALMNARAB9ATSHR | |
| SCHEMBL9383256 | 0.79 | TRPA1 (0.39) | LMNARAB9A | |
| SCHEMBL8548719 | 0.79 | MRGPRX1 (0.40) | LMNARAB9ATSHR | |
| SCHEMBL8541261 | 0.79 | ELOVL1 (0.36) | MAPK1MAPTLMNARAB9ATSHR | |
| SCHEMBL8547515 | 0.78 | AURKA (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5326766-A | Fungicide, nematocide, insecticide, miticide | DOWELANCO | 1994-07-05 | — | — | US | claimed |
| WO-1994004526-A1 | 4-[2-(4-(2-PYRIDINYLOXY)PHENYL)ETHOXY]-QUINAZOLINE AND ANALOGUES THEREOF | DOWELANCO (US) | 1994-03-03 | — | — | WO | claimed |
| US-5326766-A | Fungicide, nematocide, insecticide, miticide | DOWELANCO | 1994-07-05 | — | — | US | disclosed |
| WO-1994004526-A1 | 4-[2-(4-(2-PYRIDINYLOXY)PHENYL)ETHOXY]-QUINAZOLINE AND ANALOGUES THEREOF | DOWELANCO (US) | 1994-03-03 | — | — | WO | disclosed |