Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.38 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | CCR2 | P41597 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MIF | P14174 | 1/20 | 0.36 |
| ▸ | APLNR | P35414 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4284583 | 0.79 | ALDH1A1 (0.36) | ALDH1A1ABCB11NR3C1CYP1A2CYP3A4 | |
| SCHEMBL9303930 | 0.76 | CYP3A4 (0.41) | ALDH1A1CYP3A4HPGDTDP1 | |
| SCHEMBL2976682 | 0.74 | ALDH1A1 (0.55) | ALDH1A1ABCB11NR3C1CYP1A2CYP3A4 | |
| SCHEMBL188261 | 0.73 | ALOX15 (0.38) | ALDH1A1ABCB11NR3C1CYP1A2CYP3A4 | |
| SCHEMBL6153417 | 0.73 | HSP90AA1 (0.37) | ALDH1A1ABCB11NR3C1CYP1A2CYP3A4 | |
| SCHEMBL30507607 | 0.71 | ALDH1A1 (0.52) | ALDH1A1ABCB11NR3C1CYP1A2CYP3A4 | |
| SCHEMBL1022261 | 0.71 | ALDH1A1 (0.52) | ALDH1A1ABCB11NR3C1CYP1A2CYP3A4 | |
| SCHEMBL1093861 | 0.71 | ABCB11 (0.32) | ALDH1A1ABCB11NR3C1CYP1A2CYP3A4 | |
| SCHEMBL3367043 | 0.70 | MIF (0.34) | ALDH1A1ABCB11NR3C1CYP1A2CYP3A4 | |
| SCHEMBL30298638 | 0.70 | MIF (0.34) | ALDH1A1ABCB11NR3C1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0577560-A1 | Substituted naphtho[1,8-de:5,4-d'e']bis[1,3]thiazines, process for their preparation and their electrically conductive charge transfer complexes | CIBA-GEIGY AG (CH) | 1994-01-05 | — | — | EP | claimed |
| US-5349062-A | Charge tranfer compounds | CIBA-GEIGY CORPORATION (US) | 1994-09-20 | — | — | US | disclosed |
| EP-0577560-A1 | Substituted naphtho[1,8-de:5,4-d'e']bis[1,3]thiazines, process for their preparation and their electrically conductive charge transfer complexes | CIBA-GEIGY AG (CH) | 1994-01-05 | — | — | EP | disclosed |