SCHEMBL9306563

SCHEMBL9306563

CC(NC(=O)Nc1ccccc1)c1ccccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 1.00
MTOR P42345 1/20 0.72
EPHX2 P34913 2/20 0.58
EPHX1 P07099 3/20 0.57
TSHR P16473 2/20 0.57
TP53 P04637 1/20 0.57
CDK9 P50750 1/20 0.57
SMN1; SMN2 Q16637 1/20 0.57
CLK4 Q9HAZ1 1/20 0.57
CASR P41180 1/20 0.57
CYP2C9 P11712 1/20 0.56
NAMPT P43490 1/20 0.56
ALDH1A1 P00352 1/20 0.55
CNR1 P21554 2/20 0.54
LMNA P02545 1/20 0.54
MMP9 P14780 1/20 0.53
MMP8 P22894 1/20 0.53
FLT3 P36888 1/20 0.53
MEN1 O00255 1/20 0.53
KMT2A Q03164 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9306555 1.00 HSD17B10 (1.00) HSD17B10MTOREPHX2EPHX1TSHR
SCHEMBL6054883 0.90 HSD17B10 (0.81) HSD17B10MTORSMN1; SMN2CASRCYP2C9
SCHEMBL16942602 0.90 HSD17B10 (0.81) HSD17B10MTOREPHX1CASRCYP2C9
SCHEMBL16942608 0.90 HSD17B10 (0.81) HSD17B10MTOREPHX1CASRCYP2C9
SCHEMBL16946640 0.90 HSD17B10 (0.81) HSD17B10MTORSMN1; SMN2CASRCYP2C9
SCHEMBL8169526 0.90 HSD17B10 (0.81) HSD17B10MTORSMN1; SMN2CASRCYP2C9
SCHEMBL23718858 0.89 HSD17B10 (0.79) HSD17B10MTOREPHX2TSHRCYP2C9
SCHEMBL11615932 0.89 HSD17B10 (0.79) HSD17B10MTOREPHX2TSHRCLK4
SCHEMBL23199937 0.89 HSD17B10 (0.79) HSD17B10MTOREPHX2TSHRCYP2C9
SCHEMBL3461830 0.89 HSD17B10 (0.79) HSD17B10MTORCASRCYP2C9NAMPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117946033-A Preparation method for photo-promoted synthesis of urea compound 兰州大学 2024-04-30 CN claimed
JP-6072811-A None JP disclosed
US-20260131007-A1 Mannose 6-Phosphate Receptor Binding Compounds for the Degradation of Extracellular Proteins AVILAR THERAPEUTICS, INC. (US) 2026-05-14 US disclosed
US-12544371-B2 Methods and compositions for treating acute lung injury and acute respiratory distress syndrome CALCIMEDICA, INC. (US) 2026-02-10 US disclosed
US-20250223280-A1 POTENT ASGPR-BINDING COMPOUNDS FOR THE DEGRADATION OF IMMUNOGLOBULINS AND OTHER PROTEINS AVILAR THERAPEUTICS, INC. (US) 2025-07-10 US disclosed
EP-3949000-B1 LITHIUM BATTERY COMPRISING A UREA-BASED COMPOUND AS ELECTROLYTE ADDITIVE BAYERISCHE MOTOREN WERKE AG (DE) 2025-04-30 EP disclosed
US-12280116-B2 ASGPR-binding compounds for the degradation of extracellular proteins AVILAR THERAPEUTICS, INC. (US) 2025-04-22 US disclosed
US-20250120969-A1 METHODS AND COMPOSITIONS FOR TREATING INFLAMMATION INJURY IN THE LUNGS AVENUE CAPITAL MANAGEMENT II, L.P. 2025-04-17 US disclosed
US-20240307546-A1 ASGPR-BINDING COMPOUNDS FOR THE DEGRADATION OF EXTRACELLULAR PROTEINS AVILAR THERAPEUTICS, INC. (US) 2024-09-19 US disclosed
CN-117946033-A Preparation method for photo-promoted synthesis of urea compound 兰州大学 2024-04-30 CN disclosed
US-20220173435-A1 LITHIUM BATTERY AND USE OF A UREA-BASED ELECTROLYTE ADDITIVE AS AN ELECTROLYTE ADDITIVE THEREIN BAYERISCHE MOTOREN WERKE AKTIENGESELLSCHAFT (DE) 2022-06-02 US disclosed
EP-3949000-A1 LITHIUM BATTERY AND USE OF A UREA-BASED ADDITIVE AS AN ELECTROLYTE ADDITIVE CONTAINED THEREIN Bayerische Motoren Werke Aktiengesellschaft (DE) 2022-02-09 EP disclosed
EP-3947352-A1 COMPLEMENT MODULATORS AND RELATED METHODS RA Pharmaceuticals, Inc. (US) 2022-02-09 EP disclosed
CN-114026729-A Lithium battery and use of urea-based additives as electrolyte additives therein 宝马股份公司 2022-02-08 CN disclosed
WO-2021189013-A1 METHODS AND COMPOSITIONS FOR TREATING ACUTE LUNG INJURY AND ACUTE RESPIRATORY DISTRESS SYNDROME CALCIMEDICA, INC. (US) 2021-09-23 WO disclosed
CN-110878035-B Method for preparing symmetrical urea compound 中国科学院化学研究所 2021-01-05 CN disclosed
WO-2020205501-A1 COMPLEMENT MODULATORS AND RELATED METHODS RA PHARMACEUTICALS, INC. (US) 2020-10-08 WO disclosed
CN-110878035-A Method for preparing symmetrical urea compound 中国科学院化学研究所 2020-03-13 CN disclosed
JP-H0672811-A HERBICIDE FOR PADDY RICE HAVING DECREASED PHYTOTOXICITY SDS BIOTECH KK 1994-03-15 JP disclosed
JP-H00672811-A 0001-01-01 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12544371-B2 Methods and compositions for treating acute lung injury and acute respiratory distress syndrome ORAI1, MAVS, CASR HSD17B10 4101/4885MTOR 226/4885EPHX2 2544/4885
US-20250223280-A1 POTENT ASGPR-BINDING COMPOUNDS FOR THE DEGRADATION OF IMMUNOGLOBULINS AND OTHER PROTEINS ASGR1, FCGR2A, FCGR3B HSD17B10 3539/4885MTOR 4235/4885EPHX2 2626/4885
US-20250120969-A1 METHODS AND COMPOSITIONS FOR TREATING INFLAMMATION INJURY IN THE LUNGS IL1B, MAVS, MMP8 HSD17B10 3880/4885MTOR 1264/4885EPHX2 2452/4885
US-20260131007-A1 Mannose 6-Phosphate Receptor Binding Compounds for the Degradation of Extracellular Proteins IGF2R, M6PR, MSR1 HSD17B10 4267/4885MTOR 2504/4885EPHX2 3141/4885
US-12280116-B2 ASGPR-binding compounds for the degradation of extracellular proteins ASGR1, ENGASE, FCGR2A HSD17B10 3664/4885MTOR 4021/4885EPHX2 1875/4885
US-20240307546-A1 ASGPR-BINDING COMPOUNDS FOR THE DEGRADATION OF EXTRACELLULAR PROTEINS ASGR1, ENGASE, FCGR2A HSD17B10 3664/4885MTOR 4021/4885EPHX2 1875/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.