Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 6/20 | 0.37 |
| ▸ | RAB9A | P51151 | 6/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | DAO | P14920 | 2/20 | 0.36 |
| ▸ | DDO | Q99489 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.35 |
| ▸ | RELA | Q04206 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | FEN1 | P39748 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28412208 | 0.79 | PSMD14 (0.33) | NPC1RAB9AALDH1A1PKMSMN1; SMN2 | |
| SCHEMBL23278130 | 0.79 | CA12 (0.42) | CA12CA9PARP1NPC1RAB9A | |
| SCHEMBL12778711 | 0.76 | CA12 (0.40) | CA12CA9PARP1NPC1RAB9A | |
| SCHEMBL9187598 | 0.76 | MAPT (0.37) | PARP1NPC1RAB9AALDH1A1L3MBTL1 | |
| SCHEMBL9306986 | 0.76 | ACHE (0.43) | PARP1RAB9AALDH1A1HPGDTDP1 | |
| SCHEMBL9305632 | 0.76 | CA12 (0.40) | CA12CA9PARP1NPC1RAB9A | |
| SCHEMBL9305370 | 0.76 | NOS1 (0.41) | CA12CA9DYRK1ATYMS | |
| SCHEMBL2104559 | 0.76 | AR (0.33) | PARP1 | |
| SCHEMBL5142221 | 0.76 | PARP1 (0.59) | CA12CA9PARP1NPC1RAB9A | |
| SCHEMBL31122397 | 0.76 | NUDT1 (0.48) | CA12CA9PARP1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102702171-B | Process for producing acid adduct salt of polyacidic base compound | KOWA CO | 2014-09-10 | — | — | CN | disclosed |
| CN-102702171-A | Process for producing acid adduct salt of polyacidic base compound | KOWA CO | 2012-10-03 | — | — | CN | disclosed |
| CN-1753886-B | Method for producing acid addition salt of polybasic base compound | KOWA CO | 2012-07-18 | — | — | CN | disclosed |
| CN-101899007-B | piperazine compounds | KOWA CO | 2012-04-25 | — | — | CN | disclosed |
| CN-101328152-B | Piperazidine compound and pyridine compound | KOWA CO | 2011-06-08 | — | — | CN | disclosed |
| CN-101899007-A | Pyridine compound | KOWA CO | 2010-12-01 | — | — | CN | disclosed |
| CN-101328152-A | Piperazidine compound and pyridine compound | KOWA CO (JP) | 2008-12-24 | — | — | CN | disclosed |
| CN-100404529-C | 2, 4-bis (trifluoroethoxy) pyridine compound and medicine containing the same | KOWA CO (JP) | 2008-07-23 | — | — | CN | disclosed |
| CN-1324033-C | Thieno [2, 3-d ] pyrimidinediones and their use in the modulation of autoimmune diseases | ASTRAZENECA AB (SE) | 2007-07-04 | — | — | CN | disclosed |
| CN-1816542-A | 2, 4-bis (trifluoroethoxy) pyridine compound and medicine containing the same | KOWA CO (JP) | 2006-08-09 | — | — | CN | disclosed |
| CN-1753886-A | Method for producing acid addition salt of polybasic base compound | KOWA CO (JP) | 2006-03-29 | — | — | CN | disclosed |
| CN-1538970-A | Thieno [2, 3-d ] pyrimidinediones and their use in the modulation of autoimmune diseases | — | 2004-10-20 | — | — | CN | disclosed |
| US-5347008-A | Thio(cyclo) alkanepolycarboxylic acids containing heterocyclic substituents | CIBA-GEIGY CORPORATION (US) | 1994-09-13 | — | — | US | disclosed |
| US-4652653-A | Process for the preparation of β-(benzothiazolylthio)- and β-(benzimidazolylthio)-carboxylic acid derivatives | CIBA-GEIGY CORPORATION (US) | 1987-03-24 | — | — | US | disclosed |
| US-4612378-A | Process for the preparation of β-(benzothiazolylthio)- and β-(benzimidazolylthio-carboxylic acids | CIBA-GEIGY CORPORATION (US) | 1986-09-16 | — | — | US | disclosed |