Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 16/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.35 |
| ▸ | USP1 | O94782 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9309991 | 0.88 | ALOX5 (0.46) | ALOX5CYP2D6HRH3BRPF1 | |
| SCHEMBL9308523 | 0.86 | ALOX5 (0.62) | ALOX5CYP2D6HRH3 | |
| SCHEMBL9308988 | 0.84 | ALOX5 (0.35) | ALOX5CYP2D6 | |
| SCHEMBL9309603 | 0.82 | ALOX5 (0.60) | ALOX5CYP2D6HRH3 | |
| SCHEMBL9309969 | 0.78 | ALOX5 (0.43) | ALOX5BRPF1 | |
| SCHEMBL9389965 | 0.76 | ALOX5 (0.40) | ALOX5BRPF1 | |
| SCHEMBL9308663 | 0.74 | ALOX5 (0.48) | ALOX5CYP2D6USP1 | |
| SCHEMBL9309515 | 0.71 | SLC6A2 (0.32) | — | |
| SCHEMBL9310079 | 0.69 | ALOX5 (0.45) | ALOX5BRPF1 | |
| SCHEMBL9308680 | 0.68 | ALOX5 (0.52) | ALOX5CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5354865-A | Enzyme inhibitor and inhibiting the leukotriene biosynthesis | ABBOTT LABORATORIES (US) | 1994-10-11 | — | — | US | disclosed |