Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | HTR3A | P46098 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
| ▸ | TACR1 | P25103 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9308988 | 0.86 | ALOX5 (0.35) | SLC6A2SLC6A4HTR3AKCNH2DRD2 | |
| SCHEMBL9309991 | 0.83 | ALOX5 (0.46) | — | |
| SCHEMBL9308150 | 0.73 | MGLL (0.34) | — | |
| SCHEMBL9308141 | 0.71 | ALOX5 (0.47) | — | |
| SCHEMBL9308680 | 0.71 | ALOX5 (0.52) | — | |
| SCHEMBL9307455 | 0.69 | GRM4 (0.35) | — | |
| SCHEMBL8953917 | 0.65 | ALOX5 (0.38) | DRD2 | |
| SCHEMBL8953855 | 0.64 | RORC (0.31) | — | |
| SCHEMBL9309282 | 0.64 | ALOX5 (0.48) | — | |
| SCHEMBL28179912 | 0.64 | CTSL (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5354865-A | Enzyme inhibitor and inhibiting the leukotriene biosynthesis | ABBOTT LABORATORIES (US) | 1994-10-11 | — | — | US | disclosed |
| WO-1994005281-A1 | PHENYLMETHYL DERIVATIVES HAVING LIPOXYGENASE INHIBITORY ACTIVITY | ABBOTT LABORATORIES (US) | 1994-03-17 | — | — | WO | disclosed |