Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9308911 | 0.94 | PPARG (0.41) | PPARGAGTR1 | |
| SCHEMBL9309739 | 0.92 | PPARG (0.39) | PPARG | |
| SCHEMBL9308512 | 0.90 | PPARG (0.45) | PPARGAGTR1 | |
| SCHEMBL9308516 | 0.89 | PPARG (0.44) | PPARGAGTR1 | |
| SCHEMBL9308631 | 0.88 | CYP19A1 (0.41) | PPARG | |
| SCHEMBL9308652 | 0.87 | PPARG (0.43) | PPARGAGTR1 | |
| SCHEMBL1894428 | 0.85 | PPARG (0.50) | PPARGAGTR1 | |
| SCHEMBL9308992 | 0.84 | CYP1A2 (0.45) | PPARG | |
| SCHEMBL9307715 | 0.84 | PPARG (0.49) | PPARGAGTR1 | |
| SCHEMBL9310316 | 0.83 | ALDH1A1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5358950-A | Useful in treatment of cardiovascular diseases | LABORATOIRES UPSA (FR) | 1994-10-25 | — | — | US | disclosed |
| US-5217973-A | Treatment of cardiovascular diseases such as hypertension, cardiac insufficiency and diseases of the arterial walls | LABORATOIRES UPSA (FR) | 1993-06-08 | — | — | US | disclosed |