Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.41 |
| ▸ | XDH | P47989 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 2/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.34 |
| ▸ | WNT3A | P56704 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9308565 | 0.88 | PPARG (0.45) | PPARG | |
| SCHEMBL9308911 | 0.82 | PPARG (0.41) | ALDH1A1HPGDSMN1; SMN2PPARGNPSR1 | |
| SCHEMBL9309739 | 0.80 | PPARG (0.39) | XDHALDH1A1HPGDHTTPPARG | |
| SCHEMBL9310316 | 0.79 | ALDH1A1 (0.31) | ALDH1A1HPGDHTTSMN1; SMN2NPSR1 | |
| SCHEMBL9311134 | 0.79 | AGTR1 (0.35) | — | |
| SCHEMBL9308512 | 0.78 | PPARG (0.45) | ALDH1A1HPGDHTTSMN1; SMN2PPARG | |
| SCHEMBL9309497 | 0.77 | CYP1A2 (0.46) | CYP19A1XDHALDH1A1PPARGGRM5 | |
| SCHEMBL9308516 | 0.77 | PPARG (0.44) | ALDH1A1HPGDHTTSMN1; SMN2PPARG | |
| SCHEMBL9308971 | 0.76 | CYP19A1 (0.39) | CYP19A1 | |
| SCHEMBL9308652 | 0.76 | PPARG (0.43) | ALDH1A1HPGDHTTSMN1; SMN2PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5358950-A | Useful in treatment of cardiovascular diseases | LABORATOIRES UPSA (FR) | 1994-10-25 | — | — | US | disclosed |