Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 13/20 | 0.48 |
| ▸ | PRKDC | P78527 | 1/20 | 0.42 |
| ▸ | F10 | P00742 | 1/20 | 0.40 |
| ▸ | TLR4 | O00206 | 1/20 | 0.39 |
| ▸ | TLR2 | O60603 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9308680 | 0.77 | ALOX5 (0.52) | ALOX5PRKDCTLR4TLR2 | |
| SCHEMBL9309282 | 0.74 | ALOX5 (0.48) | ALOX5PRKDC | |
| SCHEMBL9308093 | 0.72 | MRGPRX4 (0.51) | ALOX5 | |
| SCHEMBL9308170 | 0.71 | ALOX5 (0.52) | ALOX5PRKDC | |
| SCHEMBL9308599 | 0.71 | ALOX5 (0.45) | ALOX5PRKDC | |
| SCHEMBL25890731 | 0.69 | ALOX5 (0.51) | ALOX5 | |
| SCHEMBL25890274 | 0.67 | ALOX5 (0.51) | ALOX5 | |
| SCHEMBL9136374 | 0.67 | ALOX5 (0.71) | ALOX5 | |
| SCHEMBL9135427 | 0.67 | ALOX5 (0.71) | ALOX5 | |
| SCHEMBL12938497 | 0.66 | ALOX5 (0.78) | ALOX5TLR4TLR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994005281-A1 | PHENYLMETHYL DERIVATIVES HAVING LIPOXYGENASE INHIBITORY ACTIVITY | ABBOTT LABORATORIES (US) | 1994-03-17 | — | — | WO | claimed |
| US-5354865-A | Enzyme inhibitor and inhibiting the leukotriene biosynthesis | ABBOTT LABORATORIES (US) | 1994-10-11 | — | — | US | disclosed |