Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 2/20 | 0.31 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.31 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9309904 | 0.89 | MAPK1 (0.36) | AGTR1AGTR2ADORA2BCYP1A2CYP2C9 | |
| SCHEMBL9310339 | 0.88 | KDM4E (0.33) | AGTR1AGTR2ADORA2BCYP1A2CYP2C9 | |
| SCHEMBL8545688 | 0.85 | ALDH1A1 (0.38) | ADORA2B | |
| SCHEMBL9310217 | 0.85 | — | — | |
| SCHEMBL9311392 | 0.83 | AGTR1 (0.38) | AGTR1AGTR2 | |
| SCHEMBL9309677 | 0.82 | MAPK1 (0.37) | ADORA2BCYP1A2CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL9308209 | 0.81 | AGTR1 (0.39) | AGTR1AGTR2 | |
| SCHEMBL9309667 | 0.80 | AGTR1 (0.41) | AGTR1AGTR2 | |
| SCHEMBL9317908 | 0.80 | ALDH1A1 (0.35) | — | |
| SCHEMBL9309605 | 0.80 | MAPK1 (0.36) | CYP1A2CYP2C9CYP2C19SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5374646-A | Treatment or prophylasix of hypertension and diseases associated with cognitive disorders | GLAXO GROUP LIMITED (GB) | 1994-12-20 | — | — | US | disclosed |