Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | ALB | P02768 | 2/20 | 0.58 |
| ▸ | BLM | P54132 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.58 |
| ▸ | TK1 | P04183 | 4/20 | 0.48 |
| ▸ | TYMP | P19971 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9025958 | 0.90 | LMNA (0.52) | LMNAALBBLMALDH1A1POLB | |
| SCHEMBL9024558 | 0.90 | LMNA (0.52) | LMNAALBBLMALDH1A1POLB | |
| SCHEMBL10746824 | 0.86 | ALDH1A1 (0.52) | LMNAALBBLMALDH1A1POLB | |
| SCHEMBL10757124 | 0.83 | ALDH1A1 (0.49) | LMNAALBBLMALDH1A1POLB | |
| SCHEMBL9311377 | 0.80 | LMNA (0.53) | LMNAPMP22 | |
| SCHEMBL9310440 | 0.80 | TK1 (0.56) | LMNAALBBLMALDH1A1POLB | |
| SCHEMBL8797234 | 0.79 | TK1 (0.54) | LMNAALBBLMALDH1A1POLB | |
| SCHEMBL8536692 | 0.79 | TK1 (0.54) | LMNAALBBLMALDH1A1POLB | |
| SCHEMBL9144034 | 0.79 | TYMP (0.62) | LMNAALBBLMALDH1A1POLB | |
| SCHEMBL8689341 | 0.79 | TK1 (0.54) | LMNAALBBLMALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5374625-A | Bis/hydroxymethyl/cycloalkyl derivatives; viricides | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1994-12-20 | — | — | US | disclosed |
| EP-0468352-A2 | Novel nucleic acid derivatives | Nippon Kayaku Kabushiki Kaisha (JP) | 1992-01-29 | — | — | EP | disclosed |