Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | EGLN1 | Q9GZT9 | 8/20 | 0.52 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | MMP2 | P08253 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | GMNN | O75496 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | MMP9 | P14780 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | MMP8 | P22894 | 1/20 | 0.52 |
| ▸ | CCR1 | P32246 | 1/20 | 0.52 |
| ▸ | THPO | P40225 | 1/20 | 0.52 |
| ▸ | MTOR | P42345 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1714944 | 0.86 | BCHE (0.49) | ALDH1A1EGLN1HSP90AA1KDM4EMMP2 | |
| SCHEMBL31055818 | 0.85 | BCHE (0.48) | ALDH1A1EGLN1HSP90AA1KDM4EMMP2 | |
| SCHEMBL1824345 | 0.85 | BCHE (0.48) | ALDH1A1EGLN1HSP90AA1KDM4EMMP2 | |
| SCHEMBL1240579 | 0.82 | BCHE (0.46) | ALDH1A1EGLN1HSP90AA1KDM4EMMP2 | |
| SCHEMBL10705017 | 0.82 | TRPV1 (0.49) | ALDH1A1EGLN1HSP90AA1KDM4EMMP2 | |
| SCHEMBL15334550 | 0.82 | BCHE (0.46) | ALDH1A1EGLN1HSP90AA1KDM4EMMP2 | |
| SCHEMBL12722433 | 0.82 | CTSB (0.53) | ALDH1A1EGLN1HSP90AA1KDM4EMMP2 | |
| SCHEMBL31307163 | 0.82 | BCHE (0.46) | ALDH1A1EGLN1HSP90AA1KDM4EMMP2 | |
| SCHEMBL2359289 | 0.82 | LMNA (0.52) | ALDH1A1EGLN1HSP90AA1KDM4EMMP2 | |
| SCHEMBL8934158 | 0.81 | BCHE (0.48) | ALDH1A1EGLN1HSP90AA1KDM4EMMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5294519-A | Process for preparing printed-circuit board | KANSAI PAINT CO., LTD. (JP) | 1994-03-15 | — | — | US | claimed |
| US-20170334861-A1 | TETRAHYDRO- AND DIHYDRO-ISOQUINOLINE PRMT5 INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2017-11-23 | — | — | US | disclosed |
| US-9302993-B2 | 8-hydroxy quinoline derivatives | PRANA BIOTECHNOLOGY LIMITED (AU) | 2016-04-05 | — | — | US | disclosed |
| US-20150335635-A1 | 8-HYDROXY QUINOLINE DERIVATIVES | PRANA BIOTECHNOLOGY LIMITED (AU) | 2015-11-26 | — | — | US | disclosed |
| CN-101412775-B | Catalyst precursor for polymerization of propylene or combined polymerization, and preparation thereof | BEIJING JINDINGKE CHEMICAL TECHNOLOGY CO LTD | 2010-12-22 | — | — | CN | disclosed |
| CN-101139407-B | Catalyst precursor for ethylene polymerization or copolymerization and preparation method thereof | BEIJING JINDINGKE CHEMICAL TECHNOLOGY CO LTD | 2010-10-06 | — | — | CN | disclosed |
| CN-101412775-A | Catalyst activity component for polymerization of propylene or combined polymerization, catalyst precursor containing the same and preparation thereof | BEIJING JINDINGKE CHEMICAL TEC (CN) | 2009-04-22 | — | — | CN | disclosed |
| US-20080312435-A1 | Imine Compound | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2008-12-18 | — | — | US | disclosed |
| CN-101139407-A | Catalyst active component for ethylene polymerization or copolymerization and catalyst precursor comprising the active component and preparation method thereof | BEIJING JINDINGKE CHEMICAL TEC (CN) | 2008-03-12 | — | — | CN | disclosed |
| US-5294519-A | Process for preparing printed-circuit board | KANSAI PAINT CO., LTD. (JP) | 1994-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080312435-A1 | Imine Compound | CNR1, CNR2, HRH4 | ALDH1A1 2674/4885EGLN1 1998/4885HSP90AA1 2112/4885 |
| US-20150335635-A1 | 8-HYDROXY QUINOLINE DERIVATIVES | PARK7, COQ8A, NLN | ALDH1A1 725/4885EGLN1 1896/4885HSP90AA1 1187/4885 |
| US-20170334861-A1 | TETRAHYDRO- AND DIHYDRO-ISOQUINOLINE PRMT5 INHIBITORS AND USES THEREOF | PRMT5, PRMT1, PRMT3 | ALDH1A1 1890/4885EGLN1 430/4885HSP90AA1 4331/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.