SCHEMBL9315208

SCHEMBL9315208

O=P(Oc1ccccc1S(=O)(=O)Cl)(Oc1ccccc1S(=O)(=O)Cl)Oc1ccccc1S(=O)(=O)Cl

nearest known ligand 0.38

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TRPV4 Q9HBA0 3/20 0.38
ELANE P08246 1/20 0.37
LMNA P02545 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
ALDH1A1 P00352 2/20 0.37
HSD17B10 Q99714 2/20 0.37
TDP1 Q9NUW8 1/20 0.37
HTR6 P50406 1/20 0.35
SRC P12931 1/20 0.32
KDM4E B2RXH2 1/20 0.32
USP2 O75604 1/20 0.32
HPGD P15428 1/20 0.32
PDE3A Q14432 1/20 0.32
INPPL1 O15357 1/20 0.31
INPP5B P32019 1/20 0.31
INPP5A Q14642 1/20 0.31
KCNH2 Q12809 1/20 0.31
NFE2L2 Q16236 1/20 0.31
GAA P10253 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9315209 0.85 INPPL1 (0.50) TRPV4ELANELMNASMN1; SMN2ALDH1A1
SCHEMBL2196909 0.80 MYC (0.38) ELANELMNASMN1; SMN2ALDH1A1HSD17B10
SCHEMBL7205989 0.79 TRPV4 (0.42) TRPV4ELANELMNAALDH1A1HSD17B10
SCHEMBL31387938 0.79 TRPV4 (0.42) TRPV4ELANELMNAALDH1A1HSD17B10
SCHEMBL29490409 0.75 HTR6 (0.60) TRPV4HTR6KCNH2NFE2L2
SCHEMBL74380 0.75 HTR6 (0.60) TRPV4HTR6KCNH2NFE2L2
SCHEMBL28618568 0.73 SRC (0.44) LMNAALDH1A1TDP1SRCKDM4E
SCHEMBL250199 0.72 ALDH1A1 (0.55) TRPV4ELANESMN1; SMN2ALDH1A1HSD17B10
SCHEMBL7804021 0.72 ELANE (0.46) TRPV4ELANESMN1; SMN2ALDH1A1HSD17B10
SCHEMBL997994 0.72 CASP1 (0.48) LMNAALDH1A1HSD17B10TDP1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5358836-A Photographic elements containing new magenta-dye-forming tris couplers EASTMAN KODAK COMPANY (US) 1994-10-25 US disclosed
US-5340708-A Photographic elements containing new dye-forming tris couplers EASTMAN KODAK COMPANY (US) 1994-08-23 US disclosed