Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Butane. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 8/20 | 0.49 |
| ▸ | RAB9A | P51151 | 7/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.49 |
| ▸ | TERT | O14746 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 6/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.38 |
| ▸ | APAF1 | O14727 | 1/20 | 0.37 |
| ▸ | NQO2 | P16083 | 1/20 | 0.37 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 7/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | USP2 | O75604 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 4/20 | 0.36 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.36 |
| ▸ | APBA1 | Q02410 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL114128 | 0.94 | NPC1 (0.47) | NPC1RAB9AL3MBTL1NLRP3TERT | |
| Hydrochloric Acid SCHEMBL29353138 | 0.94 | NPC1 (0.47) | NPC1RAB9AL3MBTL1NLRP3TERT | |
| SCHEMBL31680480 | 0.94 | NPC1 (0.47) | NPC1RAB9AL3MBTL1NLRP3TERT | |
| Hydrochloric Acid SCHEMBL15265 | 0.94 | NPC1 (0.47) | NPC1RAB9AL3MBTL1NLRP3TERT | |
| SCHEMBL12336666 | 0.91 | NPC1 (0.45) | NPC1RAB9AL3MBTL1NLRP3TERT | |
| SCHEMBL14065809 | 0.89 | NPC1 (0.45) | NPC1RAB9AL3MBTL1NLRP3TERT | |
| Hydrochloric Acid SCHEMBL20969348 | 0.86 | NPC1 (0.60) | NPC1RAB9AL3MBTL1NLRP3TERT | |
| SCHEMBL20969285 | 0.86 | NPC1 (0.60) | NPC1RAB9AL3MBTL1NLRP3TERT | |
| SCHEMBL9279411 | 0.86 | NPC1 (0.41) | NPC1RAB9AL3MBTL1NLRP3TERT | |
| Hydrochloric Acid SCHEMBL865599 | 0.84 | NPC1 (0.74) | NPC1RAB9AL3MBTL1NLRP3TERT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7872130-B2 | Mixture of oligomeric phenazinium compounds and acid bath for electrolytically depositing a copper deposit | ATOTECH DEUTSCHLAND GMBH (DE) | 2011-01-18 | — | — | US | disclosed |
| EP-1592825-B1 | MIXTURE OF OLIGOMERIC PHENAZINIUM COMPOUNDS AND ACID BATH FOR ELECTROLYTICALLY DEPOSITING A COPPER DEPOSIT | ATOTECH DEUTSCHLAND GMBH (DE) | 2009-03-25 | — | — | EP | disclosed |
| US-20060226021-A1 | Mixture of oligomeric phenazinium compounds and acid bath for electrolytically depositing a copper deposit | ATOTECH USA, LLC | 2006-10-12 | — | — | US | disclosed |
| EP-1592825-A1 | MIXTURE OF OLIGOMERIC PHENAZINIUM COMPOUNDS AND ACID BATH FOR ELECTROLYTICALLY DEPOSITING A COPPER DEPOSIT | ATOTECH Deutschland GmbH (DE) | 2005-11-09 | — | — | EP | disclosed |
| WO-2004057061-A1 | MIXTURE OF OLIGOMERIC PHENAZINIUM COMPOUNDS AND ACID BATH FOR ELECTROLYTICALLY DEPOSITING A COPPER DEPOSIT | ATOTECH DEUTSCHLAND GMBH (DE) | 2004-07-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060226021-A1 | Mixture of oligomeric phenazinium compounds and acid bath for electrolytically depositing a copper deposit | PICALM, ATP1A2, RAB5IF | NPC1 4091/4885RAB9A 3373/4885L3MBTL1 4752/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.