Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.35 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | XBP1 | P17861 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14159845 | 0.82 | LMNA (0.42) | ALDH1A1MAPTHTTSMN1; SMN2LMNA | |
| SCHEMBL2245372 | 0.71 | FFAR3 (0.42) | ALDH1A1MAPTHTT | |
| SCHEMBL11473105 | 0.67 | ALDH1A1 (0.39) | ALDH1A1MAPTHTTLMNAHPGD | |
| SCHEMBL638075 | 0.65 | MAPT (0.36) | ALDH1A1MAPTHTTLMNACYP2C19 | |
| SCHEMBL21895986 | 0.65 | TSHR (0.34) | ALDH1A1MAPTSMN1; SMN2LMNAHPGD | |
| SCHEMBL8535808 | 0.63 | LMNA (0.40) | ALDH1A1MAPTSMN1; SMN2LMNAHPGD | |
| SCHEMBL9316276 | 0.61 | CYP2D6 (0.35) | ALDH1A1MAPTHTTSMN1; SMN2LMNA | |
| SCHEMBL9316278 | 0.61 | CYP2D6 (0.35) | ALDH1A1MAPTHTTSMN1; SMN2LMNA | |
| SCHEMBL8007148 | 0.61 | OPRM1 (0.38) | ALDH1A1SMN1; SMN2KMT2AMEN1NPC1 | |
| SCHEMBL10356257 | 0.61 | LMNA (0.46) | MAPTHTTLMNAHPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0523151-B1 | TRANSMETALATIONS FROM ZIRCONIUM TO COPPER INTERMEDIATES | UNIV CALIFORNIA (US) | 1994-12-28 | — | — | EP | disclosed |
| US-5286889-A | Reacting 1-alkyne with zirconocene chloride hydride, reacting product with organic lithium compound, reacting with lithium cuprate compound | REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1994-02-15 | — | — | US | disclosed |
| EP-0523151-A1 | TRANSMETALATIONS FROM ZIRCONIUM TO COPPER INTERMEDIATES. | UNIV CALIFORNIA (US) | 1993-01-20 | — | — | EP | disclosed |
| US-5166382-A | Complexing to produce intermediates in preparation of vinylic side chains | REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1992-11-24 | — | — | US | disclosed |
| US-5072010-A | Reacting zirconium and lithium compounds, reacting product with copper/lithium complex | UNIVERSITY OF CALIFORNIA (US) | 1991-12-10 | — | — | US | disclosed |
| WO-1991015493-A1 | TRANSMETALATIONS FROM ZIRCONIUM TO COPPER INTERMEDIATES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1991-10-17 | — | — | WO | disclosed |