SCHEMBL9317356

SCHEMBL9317356

C=CC(=O)OCCN(C)c1ccc(C=Cc2ccc(S(=O)(=O)c3ccccc3)cc2)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.44
THRB P10828 1/20 0.40
CTDSP1 Q9GZU7 1/20 0.39
HDAC8 Q9BY41 2/20 0.39
HDAC1 Q13547 1/20 0.39
SMN1; SMN2 Q16637 2/20 0.38
GAA P10253 1/20 0.38
MAPT P10636 1/20 0.38
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
L3MBTL1 Q9Y468 1/20 0.36
HTR2A P28223 2/20 0.36
HTR2C P28335 1/20 0.36
KCNH2 Q12809 1/20 0.36
F13A1 P00488 1/20 0.36
TGM2 P21980 1/20 0.36
TGM1 P22735 1/20 0.36
HDAC6 Q9UBN7 1/20 0.35
RAB9A P51151 1/20 0.35
RELA Q04206 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9317354 1.00 ALDH1A1 (0.44) ALDH1A1THRBCTDSP1HDAC8HDAC1
SCHEMBL9317458 0.92 ALDH1A1 (0.39) ALDH1A1THRBCTDSP1HDAC8HDAC1
SCHEMBL9317451 0.92 ALDH1A1 (0.39) ALDH1A1THRBCTDSP1HDAC8HDAC1
SCHEMBL9661193 0.88 THRB (0.40) ALDH1A1THRBSMN1; SMN2GAAMAPT
SCHEMBL9661188 0.88 THRB (0.40) ALDH1A1THRBSMN1; SMN2GAAMAPT
SCHEMBL9317586 0.86 CTDSP1 (0.39) ALDH1A1CTDSP1HDAC8HDAC1SMN1; SMN2
SCHEMBL9317582 0.86 CTDSP1 (0.39) ALDH1A1CTDSP1HDAC8HDAC1SMN1; SMN2
SCHEMBL9317088 0.80 MMP14 (0.41) ALDH1A1THRBSMN1; SMN2GAAMAPT
SCHEMBL9317316 0.80 ALDH1A1 (0.38) ALDH1A1THRBCTDSP1SMN1; SMN2MEN1
SCHEMBL9317317 0.80 ALDH1A1 (0.38) ALDH1A1THRBCTDSP1SMN1; SMN2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5322986-A Methods for preparing polymer stripe waveguides and polymer stripe waveguides prepared thereby EASTMAN KODAK COMPANY (US) 1994-06-21 US disclosed
US-5157541-A Support with dielectric, reflection metal, polymeric electrooptical layers, couterelectrode EASTMAN KODAK COMPANY (US) 1992-10-20 US disclosed
US-5075796-A OPTICAL ARTICLE FOR MULTICOLOR IMAGING EASTMAN KODAK COMPANY (US) 1991-12-24 US disclosed
EP-0422725-A2 High x(2) optical article EASTMAN KODAK COMPANY (US) 1991-04-17 EP disclosed
EP-0422723-A2 Optical article for reflection modulation EASTMAN KODAK COMPANY (US) 1991-04-17 EP disclosed
US-4948225-A REFLECTIVE METAL LAYER, DIELECTRICS, PROTECTIVE COATING EASTMAN KODAK COMPANY (US) 1990-08-14 US disclosed