Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.35 |
| ▸ | ACHE | P22303 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.33 |
| ▸ | NQO2 | P16083 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28040456 | 0.78 | TSHR (0.33) | ALOX12ACHELMNATSHRALDH1A1 | |
| SCHEMBL2453373 | 0.78 | TSHR (0.43) | TDP1CYP2A6ALOX12ACHELMNA | |
| SCHEMBL28040487 | 0.78 | CYP1A2 (0.36) | CYP2A6ALOX12ACHELMNATSHR | |
| SCHEMBL9318204 | 0.74 | ACHE (0.56) | TDP1CYP2A6ALOX12ACHELMNA | |
| SCHEMBL28040846 | 0.74 | CYP1A2 (0.40) | CYP2A6ALOX12ACHELMNATSHR | |
| SCHEMBL28040867 | 0.74 | TSHR (0.37) | CYP2A6ALOX12ACHELMNATSHR | |
| SCHEMBL2454184 | 0.73 | ACHE (0.42) | TDP1CYP2A6TP53ALOX12ACHE | |
| SCHEMBL9317664 | 0.73 | ACHE (0.52) | TDP1CYP2A6TP53ALOX12ACHE | |
| SCHEMBL31590141 | 0.71 | KDM4E (0.32) | ACHETSHRALDH1A1POLBMAPT | |
| SCHEMBL28823591 | 0.71 | KDM4E (0.32) | ACHETSHRALDH1A1POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0314327-B1 | Method of producing polysilane compounds | MITSUI PETROCHEMICAL IND (JP) | 1994-01-05 | — | — | EP | disclosed |
| US-5089648-A | Using tetrakis/triethylphosphine/nickel polymerization catalyst | ETHYL CORPORATION (US) | 1992-02-18 | — | — | US | disclosed |
| US-5089646-A | Polysilane precursors | ETHYL CORPORATION (US) | 1992-02-18 | — | — | US | disclosed |
| US-5047569-A | POLYMERIZING MONOMERIC OR PRECURSOR IN PRESENCE OF A DIPHOSPHOROUS NICKEL CHLORIDE CATALYSST | ETHYL CORPORATION (US) | 1991-09-10 | — | — | US | disclosed |
| US-5003100-A | Polysilanes and their formation using rhodium dimer catalyst | ETHYL CORPORATION (US) | 1991-03-26 | — | — | US | disclosed |
| US-4900861-A | POLYMERIZING A SILANE HAVING 2 OR 3 HYDROGENS ATTACHED USING A CATALYTIC ORGANOMETALLIC COMPLEX OF NICKEL, COBALT, RUTHENIUM, PALLADIUM OR IRIDIUM | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1990-02-13 | — | — | US | disclosed |
| EP-0314327-A2 | Method of producing polysilane compounds | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1989-05-03 | — | — | EP | disclosed |