SCHEMBL9322402

SCHEMBL9322402

C=C(C)CONc1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR174 Q9BXC1 1/20 0.49
ALDH1A1 P00352 5/20 0.39
KDM4E B2RXH2 1/20 0.39
TAS2R38 P59533 1/20 0.38
NAPRT Q6XQN6 1/20 0.38
HSD17B10 Q99714 1/20 0.38
TSHR P16473 3/20 0.37
HPGD P15428 3/20 0.37
ALOX15 P16050 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
CYP3A4 P08684 1/20 0.35
ALOX5 P09917 1/20 0.35
MAPT P10636 5/20 0.35
ALOX12 P18054 1/20 0.35
MAPK1 P28482 1/20 0.35
HTT P42858 1/20 0.35
IDO1 P14902 1/20 0.34
MAOA P21397 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL941357 0.80 NAPRT (0.47) GPR174ALDH1A1NAPRTHSD17B10TSHR
SCHEMBL28059659 0.80 GPR174 (0.35) GPR174ALDH1A1KDM4ETAS2R38HSD17B10
SCHEMBL21933079 0.75 MAPT (0.52) ALDH1A1NAPRTHSD17B10TSHRHPGD
SCHEMBL27631576 0.74 HTT (0.46) ALDH1A1KDM4ENAPRTHSD17B10TSHR
SCHEMBL941518 0.73 MAPT (0.43) ALDH1A1KDM4ENAPRTHSD17B10HPGD
SCHEMBL11313866 0.72 IDO1 (0.42) ALDH1A1TAS2R38NAPRTHSD17B10TSHR
SCHEMBL45188 0.72 KCNH3 (0.49) ALDH1A1HSD17B10TSHRHPGDALOX15
SCHEMBL8415435 0.71 THRB (0.45) GPR174ALDH1A1KDM4ENAPRTHSD17B10
SCHEMBL5395411 0.71 NPC1 (0.57) GPR174ALDH1A1KDM4EHSD17B10ALOX15
SCHEMBL942414 0.71 ALOX5 (0.49) ALDH1A1HPGDNPSR1L3MBTL1ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0379228-B1 Process for the preparation of polymers containing imide groups from bis-imides and alkenyloxyanilines CIBA GEIGY AG (CH) 1994-01-26 EP disclosed
US-5206338-A Molding materials; nontoxic; films; foams; fillers; lamination for aerospace and electrical products CIBA-GEIGY CORPORATION (US) 1993-04-27 US disclosed
EP-0274968-B1 POLYMERS CONTAINING IMIDE GROUPS PREPARED FROM STERICALLY HINDERED DIAMINES, AND PROCESS FOR THEIR PREPARATION RHONE-POULENC CHIMIE (FR) 1991-08-14 EP disclosed
EP-0231712-B1 POLYMERS WITH IMIDE GROUPS AND PROCESS FOR THEIR PREPARATION RHONE-POULENC CHIMIE (FR) 1990-10-17 EP disclosed
EP-0379228-A2 Process for the preparation of polymers containing imide groups from bis-imides and alkenyloxyanilines CIBA-GEIGY AG (CH) 1990-07-25 EP disclosed
EP-0233435-B1 POLYMERES CONTAINING IMIDES GROUPS AND PROCESS FOR THEIR PREPARATION RHONE-POULENC CHIMIE (FR) 1990-03-21 EP disclosed
US-4886868-A MOLDING MATERIALS RHONE-POULENC SPECIALITES CHIMIQUES (FR) 1989-12-12 US disclosed
US-4883883-A IMPROVED MECHANICAL PROPERTIES RHONE-POULENC CHIMIE (FR) 1989-11-28 US disclosed
EP-0208634-B1 MALEIMIDES AND THERMOHARDENING COMPOSITIONS CONTAINING THEM RHONE-POULENC CHIMIE (FR) 1989-09-06 EP disclosed
US-4839440-A IMPROVED THERMAL PROPERTIES RHONE-POULENC CHIMIE (FR) 1989-06-13 US disclosed
US-4788295-A Functional monomaleimide and thermosetting composition therefrom RHONE-POULENC SPECIALITES CHIMIQUES (FR) 1988-11-29 US disclosed
US-4777237-A HEAT-RESISTANT THERMOSETTING MOLDING MATERIALS RHONE-POULENC SPECIALITIES CHIMIQUES (FR) 1988-10-11 US disclosed
EP-0274968-A2 Polymers containing imide groups prepared from sterically hindered diamines, and process for their preparation RHONE-POULENC CHIMIE (FR) 1988-07-20 EP disclosed
EP-0273839-A2 Polyimides derived from bis-imides and alkenyl-oxyanilines RHONE-POULENC CHIMIE (FR) 1988-07-06 EP disclosed
US-4742141-A HEAT-STABLE; IMPREGNANTS; COATING OR MOLDING RESINS RHONE-POULENC SPECIALITES CHIMIQUES (FR) 1988-05-03 US disclosed
EP-0233435-A1 Polymeres containing imides groups and process for their preparation RHONE-POULENC CHIMIE (FR) 1987-08-26 EP disclosed
EP-0231712-A1 Polymers with imide groups and process for their preparation RHONE-POULENC CHIMIE (FR) 1987-08-12 EP disclosed
EP-0208634-A1 Maleimides and thermohardening compositions containing them RHONE-POULENC CHIMIE (FR) 1987-01-14 EP disclosed